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DAPK2

  • Official Full Name

    death-associated protein kinase 2

  • Overview

    This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis.It uses multiple polyadenylation sites.
  • Synonyms

    DAPK2; death-associated protein kinase 2; DRP 1; MGC119312; DAP kinase 2; DAP-kinase-related protein 1 beta isoform; DRP1; DRP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAPK2-26805TH Recombinant Human DAPK2 N/A
Human DAPK2-675H Recombinant Human Death-Associated Protein Kinase 2, His-tagged Insect Cell His
Human DAPK2-290H Recombinant Human DAPK2, GST-tagged, Active Sf9 Insect Cell GST
Human DAPK2-2339H Recombinant Human DAPK2 Protein, GST-tagged Wheat Germ GST
Human DAPK2-7076HCL Recombinant Human DAPK2 293 Cell Lysate HEK293 N/A
Human DAPK2-1237H Recombinant Human DAPK2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DAPK2-1311H Recombinant Human DAPK2 Protein, His-tagged E.coli N-His Met1-Thr235
Mouse DAPK2-4305M Recombinant Mouse DAPK2 Protein Mammalian Cell His
Mouse DAPK2-2201M Recombinant Mouse DAPK2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dapk2-2452M Recombinant Mouse Dapk2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DAPK2-2201M-B Recombinant Mouse DAPK2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DAPK2 involved in several pathways and played different roles in them. We selected most pathways DAPK2 participated on our site, such as Pathways in cancer, Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pathways in cancerFGF11;MAPK9;PIK3R3;PIK3R2;HSP90AA1;WNT10B;STAT5A;HGF;MAPK3
Bladder cancerRPS6KA5;CDK4;FGFR3;MMP9;TYMP;RAF1;MYC;UPK3A;E2F2

DAPK2 has several biochemical functions, for example, ATP binding, calmodulin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK2 itself. We selected most functions DAPK2 had, and list some proteins which have the same functions with DAPK2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNLRP4B;EPRS;XRCC5;CSNK1G2;UBA7;TTBK1;ERBB2;ABCB1;CHORDC1
calmodulin bindingCAMKV;MYH3;VAMP2;ITPKC;IQGAP3;ITPKB;CNN3;DCX;RASGRF2
identical protein bindingERN1;ATL2;TYROBP;SH3GL1;LRP6;SNCAIP;TRAF2;NIF3L1;SNX1
protein bindingCFL1;LGI1;ST8SIA5;CTSH;EXOSC1;MKRN1;CASP10;FEN1;VHL
protein serine/threonine kinase activityAURKB;SQSTM1;MAP2K2;CDC42BPB;CAMK2A;CSNK2A1;MAP3K2;CAMKK1A;BUB1B

DAPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK2.

FAM9B; Bub1; LLGL2; KLC3; TUBGCP5; RACGAP1

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