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DAZAP1

  • Official Full Name

    DAZ associated protein 1

  • Overview

    In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
  • Synonyms

    DAZAP1; DAZ associated protein 1; DAZ-associated protein 1; deleted in azoospermia associated protein 1; MGC19907; deleted in azoospermia-associated protein 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAZAP1-2357H Recombinant Human DAZAP1 Protein, GST-tagged Wheat Germ GST
Human DAZAP1-7069HCL Recombinant Human DAZAP1 293 Cell Lysate HEK293 N/A
Human DAZAP1-2544HF Recombinant Full Length Human DAZAP1 Protein, GST-tagged In Vitro Cell Free System GST 407 amino acids
Human DAZAP1-1698HFL Recombinant Full Length Human DAZAP1 Protein, C-Flag-tagged Mammalian cells Flag
Human DAZAP1-718H Recombinant Human DAZAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DAZAP1-718H-B Recombinant Human DAZAP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse DAZAP1-4312M Recombinant Mouse DAZAP1 Protein Mammalian Cell His
Mouse DAZAP1-2206M-B Recombinant Mouse DAZAP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Dazap1-2459M Recombinant Mouse Dazap1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DAZAP1-2206M Recombinant Mouse DAZAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DAZAP1-7709Z Recombinant Zebrafish DAZAP1 Mammalian Cell His
Chicken DAZAP1-3077C Recombinant Chicken DAZAP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DAZAP1 involved in several pathways and played different roles in them. We selected most pathways DAZAP1 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAZAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwaySMG5;DAZAP1;PPP2R5C;PPP2R5CB;SMG6;FIP1L1B;PABPC1A;CASC3;PPP2R3C

DAZAP1 has several biochemical functions, for example, RNA binding, RNA stem-loop binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAZAP1 itself. We selected most functions DAZAP1 had, and list some proteins which have the same functions with DAZAP1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingIMPDH2;SUPV3L1;HNRNPA1L2;RPL18;PTBP2A;RPS3A;PHAX;PPRC1;FMR1
RNA stem-loop bindingCPEB3;DAZAP1;EPRS;DDX3X
nucleotide bindingCKMB;MRPL23;STK30;EPHA4A;VMHC;MAPKAPK2A;NT5C3B;TTLL13;GRK1B
poly(A) RNA bindingRPS18;SNRPG;DIMT1;KRT18;RBM5;CPEB2;MTPAP;KIAA1967;RPS4X

DAZAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAZAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAZAP1.

SF1; ssrna_ug

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