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DCAF7

  • Official Full Name

    DDB1 and CUL4 associated factor 7

  • Overview

    Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • Synonyms

    DCAF7; DDB1 and CUL4 associated factor 7; WD repeat domain 68 , WDR68; DDB1- and CUL4-associated factor 7; HAN11; human anthocyanin; seven WD repeat protein of the AN11 family 1; SWAN 1; AN11; DCAF7_HUMAN; WD repeat domain 68; WD repeat protein An11 homolog; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WDR68; WD-repeat protein; seven-WD-repeat protein of the AN11 family-1; SWAN-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Strep
  • SUMO
  • N/A
  • No tag
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DCAF7-3624H Recombinant Human DCAF7, His-tagged Human His
Human DCAF7-30698TH Recombinant Human DCAF7, His-tagged E.coli His 277 amino acids
Human DCAF7-3012H Recombinant Human DDB1 And CUL4 Associated Factor 7, T7-tagged E.coli T7
Human DCAF7-4565H Recombinant Human DCAF7 Protein, GST-tagged Wheat Germ GST
Human DCAF7-7055HCL Recombinant Human DCAF7 293 Cell Lysate HEK293 N/A
Human DCAF7-3456HF Recombinant Full Length Human DCAF7 Protein, GST-tagged In Vitro Cell Free System GST 342 amino acids
Human DCAF7-3761H Recombinant Human DCAF7 protein, His-SUMO-tagged E.coli His-SUMO 1-342aa
Human DCAF7-0582H Recombinant Human DCAF7 Protein (S2-V342), Tag Free Insect Cell No tag S2-V342
Human DCAF7-4210H Recombinant Human DCAF7 protein, His-tagged E.coli His 1-342aa
Human DCAF7-0583H Recombinant Human DCAF7 Protein (S2-V342), His/Strep tagged Insect Cell His/Strep S2-V342
Zebrafish DCAF7-10423Z Recombinant Zebrafish DCAF7 Mammalian Cell His
Chicken DCAF7-3543C Recombinant Chicken DCAF7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DCAF7 involved in several pathways and played different roles in them. We selected most pathways DCAF7 participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCAF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
TNF-alpha/NF-kB Signaling PathwayUSP2;PDCD2;FAF1;PPP1R13L;MARK2;DAP;NR2C2;SMARCE1;TRAIP

DCAF7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCAF7 itself. We selected most functions DCAF7 had, and list some proteins which have the same functions with DCAF7. You can find most of the proteins on our site.

Function Related Protein
protein bindingANKMY2;GZMB;RPGR;TGFB2;LRFN2;ELF4;SPI1;MT1X;PRPF4B

DCAF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCAF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of DCAF7.

MAP3K1; HIPK2; DYRK1A

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does DCAF7 protein contribute to the development of drug resistance in cancer? 01/01/2022

DCAF7 protein has been implicated in promoting drug resistance in cancer cells by affecting DNA repair pathways, making it an important factor in cancer treatment resistance.

Are there any known genetic alterations in the DCAF7 gene associated with cancer susceptibility? 04/19/2021

While specific genetic alterations in the DCAF7 gene have not been extensively studied, it is possible that mutations or dysregulation of the gene may contribute to cancer susceptibility.

Is there any evidence linking DCAF7 protein to specific types of cancer? 01/24/2020

Research has suggested that DCAF7 protein may be involved in the development of various types of cancer, including breast, ovarian, and colorectal cancer.

How is the expression of DCAF7 protein assessed in clinical settings? 02/28/2019

The expression of DCAF7 protein can be assessed using immunohistochemistry or molecular techniques, which may provide valuable information for cancer prognosis and treatment planning.

Can targeting DCAF7 protein have potential implications for personalized cancer therapy? 08/28/2018

Targeting DCAF7 protein may have implications for personalized cancer therapy by exploiting specific vulnerabilities in cancer cells related to DNA repair mechanisms.

Customer Reviews (3)

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Reviews
09/06/2020

    The DCAF7 protein is a top-quality product that is sure to fulfill my experimental requirements.

    05/02/2019

      It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.

      11/02/2016

        the ease of use and compatibility of the DCAF7 protein with various techniques further enhances its appeal.

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