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DCD

  • Official Full Name

    dermcidin

  • Overview

    This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
  • Synonyms

    DCD; dermcidin; AIDD; DCD 1; diffusible survival/evasion peptide; DSEP; HCAP; PIF; preproteolysin; proteolysis inducing factor; survival promoting peptide; DCD-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Streptomyces coelicolor A3(2)
  • E. coli or Yeast
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian cells
  • Protein Conjugation
  • Wheat Germ
  • Yeast
  • Fc
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • B2M
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DCD-665H Recombinant Human DCD Protein, Fc-tagged HEK293 Fc
Human DCD-2388H Recombinant Human DCD Protein, GST-tagged Wheat Germ GST
Human DCD-8144H Recombinant Human DCD protein, His-tagged E.coli His Cys18~Leu110 (Accession # P81605)
Human DCD-7053HCL Recombinant Human DCD 293 Cell Lysate HEK293 N/A
Human DCD-2799H Recombinant Human DCD Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Lys96-Leu110
Human DCD-2798HF Recombinant Full Length Human DCD Protein, GST-tagged In Vitro Cell Free System GST 110 amino acids
Human DCD-650HFL Recombinant Full Length Human DCD Protein, C-Flag-tagged Mammalian cells Flag
Human DCD-1376H Recombinant Human DCD Protein (20-110 aa), His-tagged Yeast His 20-110 aa
Human DCD-2802H Recombinant Human DCD protein, GST-tagged E.coli GST 20-110aa
Human DCD-2803H Recombinant Human DCD protein, His-B2M-tagged E.coli His-B2M 20-110aa
Human DCD-724H Recombinant Human DCD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DCD-724H-B Recombinant Human DCD Protein Pre-coupled Magnetic Beads HEK293
Human DCD-1739H Recombinant Human DCD Protein (Cys18-Leu110), His tagged E.coli His Cys18-Leu110
Streptomyces coelicolor A3(2) DCD-1183S Recombinant Streptomyces coelicolor A3(2) DCD protein, His-tagged E. coli or Yeast His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DCD Related Articles

DCD involved in several pathways and played different roles in them. We selected most pathways DCD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DCD has several biochemical functions, for example, peptidase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCD itself. We selected most functions DCD had, and list some proteins which have the same functions with DCD. You can find most of the proteins on our site.

Function Related Protein
peptidase activityAPH1C;PM20D1.2;UNC5CL;PSMB9A;HPN;CTSH;PCSK5B;UFSP2;BMP1A
poly(A) RNA bindingWDR3;MRPL15;CNOT1;CANX;FASTKD2;BOP1;PRRC2A;DNAJC2;HLA-A
protein bindingCCDC151;OBSCN;SPTAN1;EPHA4;NTS;BPTF;PIF1;MED21;GAGE1

DCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCD here. Most of them are supplied by our site. Hope this information will be useful for your research of DCD.

APPBP2; PPP2R2B; SSSCA1; RAD51D; CD2BP2; FAM107A; VDAC1; YWHAZ; ILK; EIF2B1; TNFRSF14; INPP5K; CDC42BPB; IL24; midostaurin; MED26

Bancovik, J; Moreira, DF; et al. Dermcidin exerts its oncogenic effects in breast cancer via modulation of ERBB signaling. BMC CANCER 15:-(2015).
Sanchez-Escuredo, A; Alsina, A; et al. Polyclonal Versus Monoclonal Induction Therapy in a Calcineurin Inhibitor-Free lmmunosuppressive Therapy in Renal Transplantation: A Comparison of Efficacy and Costs. TRANSPLANTATION PROCEEDINGS 47:45-49(2015).
  • Q&As
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