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DCP1A

  • Official Full Name

    decapping mRNA 1A

  • Overview

    Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  • Synonyms

    DCP1A; decapping mRNA 1A; SMIF; SMAD4IP1; HSA275986; Nbla00360; mRNA-decapping enzyme 1A; decapping enzyme hDcp1a; transcription factor SMIF; DCP1 decapping enzyme homolog A; putative protein product of Nbla00360; Smad4-interacting transcriptional co-activator;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DCP1A-2399H Recombinant Human DCP1A Protein, GST-tagged Wheat Germ GST
Human DCP1A-7053H Recombinant Human SMAD4, GST-tagged E.coli GST Full length
Human DCP1A-7048HCL Recombinant Human DCP1A 293 Cell Lysate HEK293 N/A
Human DCP1A-4904H Recombinant Human DCP1A protein, His-tagged E.coli His 1-582aa
Human DCP1A-6648H Recombinant Human DCP1A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DCP1A-291H Recombinant Human DCP1A Protien, His-tagged E. coli His 1-350 aa
Human DCP1A-2888HF Recombinant Full Length Human DCP1A Protein, GST-tagged In Vitro Cell Free System GST 582 amino acids
Human DCP1A-2028HFL Recombinant Full Length Human DCP1A Protein, C-Flag-tagged Mammalian cells Flag
Human DCP1A-726H Recombinant Human DCP1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DCP1A-726H-B Recombinant Human DCP1A Protein Pre-coupled Magnetic Beads HEK293
Mouse DCP1A-4356M Recombinant Mouse DCP1A Protein Mammalian Cell His
Mouse Dcp1a-2476M Recombinant Mouse Dcp1a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DCP1A-2236M Recombinant Mouse DCP1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DCP1A-2236M-B Recombinant Mouse DCP1A Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DCP1A-9681Z Recombinant Zebrafish DCP1A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DCP1A Related Articles

DCP1A involved in several pathways and played different roles in them. We selected most pathways DCP1A participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCP1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationHSPA9;LSM8;PAN3;SKIV2L;PATL1;MPHOSPH6;CNOT4B;PFKMB;LSM6

DCP1A has several biochemical functions, for example, enzyme activator activity, hydrolase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCP1A itself. We selected most functions DCP1A had, and list some proteins which have the same functions with DCP1A. You can find most of the proteins on our site.

Function Related Protein
enzyme activator activityTRIM23;RAB3GAP2;RICTOR;GMFG;LTC4S;OGT;CASP9;MMP17;CTSA
hydrolase activityPPM1H;ACP5B;MBTPS2;ATP1A1A.2;PGCP;CPD;ACP5A;PPAP2C;PLA2G4AA
identical protein bindingDRG1;HOOK2;CLPP;MUL1A;TTC32;AGER;TRP53;PAK2;MYBPC3
protein bindingNAPB;YTHDC1;TRIM17;PPM1A;NLRC4;CCER1;ZFP36L1;TGFB3;SOCS2

DCP1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCP1A here. Most of them are supplied by our site. Hope this information will be useful for your research of DCP1A.

DCP2; UPF1

Menon, B; Sinden, J; et al. Association of luteinizing hormone receptor (LHR) mRNA with its binding protein leads to decapping and degradation of the mRNA in the p bodies. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:1173-1179(2013).
Osugi, K; Suzuki, H; et al. Identification of the P-body component PATL1 as a novel ALG-2-interacting protein by in silico and far-Western screening of proline-rich proteins. JOURNAL OF BIOCHEMISTRY 151:657-666(2012).
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