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DCXR

  • Official Full Name

    dicarbonyl/L-xylulose reductase

  • Overview

    The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain d;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DCXR-128H Active Recombinant Human DCXR protein, His-tagged E.coli His
Human DCXR-11874H Recombinant Human DCXR, GST-tagged E.coli GST 1-244a.a.
Human DCXR-2424H Recombinant Human DCXR Protein, GST-tagged Wheat Germ GST
Human DCXR-490H Recombinant Human DCXR, His tagged E.coli His
Human DCXR-2726H Recombinant Human Dicarbonyl/L-xylulose Reductase, His-tagged E.coli His
Human DCXR-26175TH Recombinant Human DCXR, His-tagged E.coli His 244 amino acids
Human DCXR-7030HCL Recombinant Human DCXR 293 Cell Lysate HEK293 N/A
Human DCXR-2420HF Recombinant Full Length Human DCXR Protein, GST-tagged In Vitro Cell Free System GST 244 amino acids
Human DCXR-3334H Recombinant Human DCXR protein, His-SUMO-tagged E.coli His-SUMO Met1~Cys244
Mouse Dcxr-2488M Recombinant Mouse Dcxr Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DCXR-1806R Recombinant Rat DCXR Protein Mammalian Cell His
Rat DCXR-1464R Recombinant Rat DCXR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DCXR-1464R-B Recombinant Rat DCXR Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DCXR-2390Z Recombinant Zebrafish DCXR Mammalian Cell His
Chicken DCXR-5798C Recombinant Chicken DCXR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DCXR involved in several pathways and played different roles in them. We selected most pathways DCXR participated on our site, such as Pentose and glucuronate interconversions, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCXR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pentose and glucuronate interconversionsSORD;AKR1B7;UGT1A4;UGT1A3;AKR1B1L;GUSB;OXSR1;DCXR;CRYL1
Metabolic pathwaysEXT1C;BDH1;POLA2;IVD;CKMT1B;DAO;CYP51A1;PNP6;COX6B1

DCXR has several biochemical functions, for example, L-xylulose reductase (NADP+) activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by DCXR itself. We selected most functions DCXR had, and list some proteins which have the same functions with DCXR. You can find most of the proteins on our site.

Function Related Protein
L-xylulose reductase (NADP+) activity
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorAKR1C6;AKR1C4;AKR1C2;AKR1C3;CBR1;DCXR;DHRS4;NDUFS7;AKR1C21

DCXR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCXR here. Most of them are supplied by our site. Hope this information will be useful for your research of DCXR.

DMWD; GSTK1; TRAF6; CRADD; ssrna_ac

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