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DDAH1

  • Official Full Name

    Dimethylarginine Dimethylaminohydrolase 1

  • Overview

    This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity.
  • Synonyms

    DDAH1; N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; DDAHI; DDAH-1; dimethylargininase-1; NG, NG-dimethylarginine dimethylaminohydrolase; EC 3.5.3.18; OTTHUMP00000012304; FLJ2553; FLJ21264; dimethylarginine dimethylaminohydrolase 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • Met|His
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDAH1-1063H Active Recombinant Human DDAH1 Protein, Met & His-tagged E.coli Met/His Ala2-Ser285
Human DDAH1-2846H Recombinant Human DDAH1, His-tagged E.coli His
Human DDAH1-224H Recombinant Human DDAH1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DDAH1-26449TH Recombinant Human DDAH1, His-tagged E.coli His 285 amino acids
Human DDAH1-2427H Recombinant Human DDAH1 Protein, GST-tagged Wheat Germ GST
Human DDAH1-448HCL Recombinant Human DDAH1 cell lysate N/A
Human DDAH1-2808H Recombinant Human DDAH1 protein, His&Myc-tagged E.coli His&Myc 2-285aa
Human DDAH1-2424HF Recombinant Full Length Human DDAH1 Protein, GST-tagged In Vitro Cell Free System GST 285 amino acids
Human DDAH1-2068H Recombinant Human DDAH1 Protein (Ala2-Ser285), N-His tagged E.coli N-His Ala2-Ser285
Mouse Ddah1-2489M Recombinant Mouse Ddah1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DDAH1-1808R Recombinant Rat DDAH1 Protein Mammalian Cell His
Rat DDAH1-1466R Recombinant Rat DDAH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DDAH1-1466R-B Recombinant Rat DDAH1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DDAH1-1202R Recombinant Rhesus monkey DDAH1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DDAH1-1027R Recombinant Rhesus Macaque DDAH1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DDAH1-1027R-B Recombinant Rhesus Macaque DDAH1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DDAH1-12469Z Recombinant Zebrafish DDAH1 Mammalian Cell His
Chicken DDAH1-5952C Recombinant Chicken DDAH1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DDAH1 Related Articles

DDAH1 involved in several pathways and played different roles in them. We selected most pathways DDAH1 participated on our site, such as Metabolism, Metabolism of nitric oxide, eNOS activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDAH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MetabolismCYP3C4;NDUFA11;BCKDK;ACOT2;FAAH2A;BCHE;DHODH;ACSM1;ALOX5AP
Metabolism of nitric oxideCYGB;NOSTRIN;CYGB2;NOSIP;DDAH2;ZDHHC21;GCHFR;DDAH1;LYPLA1
eNOS activationCYGB2;DDAH2;CYGB;DDAH1;CYGB1;LYPLA1;ZDHHC21
eNOS activation and regulationGCHFR;CYGB1;NOSTRIN;CYGB2;NOSIP;DDAH1;SPRB;CYGB;LYPLA1

DDAH1 has several biochemical functions, for example, amino acid binding, catalytic activity, dimethylargininase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDAH1 itself. We selected most functions DDAH1 had, and list some proteins which have the same functions with DDAH1. You can find most of the proteins on our site.

Function Related Protein
amino acid bindingTPH2;AARS;KARS;PAH;TPH1B;TH;DDC;DDAH2;AARS2
catalytic activityPPM1DB;GOT1L1;BLM;PKMA;HSD17B6;SPTLC2B;HADHAA;TIGARB;AADAC
dimethylargininase activityDDAH2;DDAH1
metal ion bindingGFI1AA;GALNT6;ANKMY2A;NT5C2A;RAF1B;PDE11A;ZNF239;ABLIM1A;ARSB

DDAH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDAH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDAH1.

der; IQCB1

Ferrigno, A; Rizzo, V; et al. Changes in ADMA/DDAH Pathway after Hepatic Ischemia/Reperfusion Injury in Rats: The Role of Bile. BIOMED RESEARCH INTERNATIONAL :-(2014).
Yokoro, M; Suzuki, M; et al. Asymmetric Dimethylarginine, an Endogenous NOS Inhibitor, Is Actively Metabolized in Rat Erythrocytes. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 76:1334-1342(2012).
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