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DDX1

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box helicase 1

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein of unknown function. It shows high transcription levels in 2 retinoblastoma cell lines and in tissues of neuroectodermal origin. [provided by RefSeq, Jul 2008]
  • Synonyms

    DDX1; DEAD (Asp-Glu-Ala-Asp) box helicase 1; DBP-RB; UKVH5d; ATP-dependent RNA helicase DDX1; DEAD box-1; DEAD box protein 1; DEAD box polypeptide 1; DEAD box protein retinoblastoma; DEAD (Asp-Glu-Ala-Asp) box polypeptide 1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX1-11888H Recombinant Human DDX1, His-tagged E.coli His C-term-350a.a.
Human DDX1-26545TH Recombinant Human DDX1 Wheat Germ N/A 740 amino acids
Human DDX1-2461H Recombinant Human DDX1 Protein, GST-tagged Wheat Germ GST
Human DDX1-7021HCL Recombinant Human DDX1 293 Cell Lysate HEK293 N/A
Human DDX1-4893H Active Recombinant Human DDX1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Human DDX1-3083H Recombinant Human DDX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DDX1-356HFL Active Recombinant Full Length Human DDX1 Protein, C-Flag-tagged Mammalian cells Flag
Human DDX1-738H-B Recombinant Human DDX1 Protein Pre-coupled Magnetic Beads HEK293
Human DDX1-119HF Recombinant Full Length Human DDX1 Protein In Vitro Cell Free System 740 amino acids
Human DDX1-2527HF Recombinant Full Length Human DDX1 Protein, GST-tagged In Vitro Cell Free System GST 740 amino acids
Human DDX1-738H Recombinant Human DDX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DDX1-4397M Recombinant Mouse DDX1 Protein Mammalian Cell His
Mouse DDX1-2261M-B Recombinant Mouse DDX1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ddx1-266M Recombinant Mouse Ddx1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse DDX1-2261M Recombinant Mouse DDX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DDX1-1816R Recombinant Rat DDX1 Protein Mammalian Cell His
Rat DDX1-1474R Recombinant Rat DDX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DDX1-1474R-B Recombinant Rat DDX1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey DDX1-454C Recombinant Cynomolgus DDX1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey DDX1-200C Recombinant Cynomolgus Monkey DDX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey DDX1-200C-B Recombinant Cynomolgus Monkey DDX1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DDX1-1212R Recombinant Rhesus monkey DDX1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DDX1-1037R-B Recombinant Rhesus Macaque DDX1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DDX1-1037R Recombinant Rhesus Macaque DDX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DDX1-7828Z Recombinant Zebrafish DDX1 Mammalian Cell His
Chicken DDX1-6132C Recombinant Chicken DDX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DDX1 involved in several pathways and played different roles in them. We selected most pathways DDX1 participated on our site, such as Aldosterone synthesis and secretion, Neuronal System, Potassium Channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aldosterone synthesis and secretionPRKD1;Adcy4;ADCY9;CREB3L4;CAMK2B;AGTR1;PRKACG;SLC14A2;CALM2
Neuronal SystemKCNA6;KCNQ3;KCNJ14;KCNAB3;RERG;CHRNA5;KCNC1;KCNJ1A.3;CACNG2B
Potassium ChannelsKCNJ14;KCNH8;KCNMB1;KCNN4;HCN4;KCNB2;KCNF1A;DDX1;KCNC3A
TWIK-releated acid-sensitive K+ channel (TASK)DDX1;KCNK3A
Tandem pore domain potassium channelsKCNK1A;KCNK7;DDX1;KCNK2B;KCNK1B;KCNK2;KCNK1;KCNK3A;KCNK13A

DDX1 has several biochemical functions, for example, S100 protein binding, ion channel activity, open rectifier potassium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX1 itself. We selected most functions DDX1 had, and list some proteins which have the same functions with DDX1. You can find most of the proteins on our site.

Function Related Protein
S100 protein bindingFGF1;ANXA2;EZR;KCNK3;DDX1;S100A6;AGER;ANXA11;S100A1
ion channel activityCHRNA2A;TRPC7B;Chrng;CLCNK;CHRNA1;KCNS3A;KCNH2A;TRPC4A;SCN11A
open rectifier potassium channel activityKCNK3A;DDX1;KCNK3
potassium channel activityKCNK3A;KCNK16;KCNC2;KCNK10;KCNQ3;KCNC1B;TMEM38B;KCNF1A;KCNJ11L
potassium ion leak channel activityKCNK13A;KCNK1B;TMEM175;KCNK1A;KCNK18;KCNK3;KCNK9;KCNK1;KCNK2
protein C-terminus bindingLIG4;CALCOCO1;VPS4A;MYO1C;NIPBL;SDCBP;ERCC6;SP1;DAB2
protein heterodimerization activityCENPW;RRAGA;ADRB1;PAFAH1B3;JAM3;BCL2L1;UGT1A4;KCNH1;BMP2
protein homodimerization activityKLHL7;HES1;PRTFDC1;OXCT1;ADD2;PDXK;TCF3A;HER5;PON1

DDX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX1.

YWHAZ; RELB; SMAD2; NDRG1; NME7; 8-aha-camp; 8-aha-omethyladenosine; ssrna_ug

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