Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

DDX11

  • Official Full Name

    DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. This gene is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Synonyms

    DDX11; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 11 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 11 (S.cerevisiae CHL1 like helicase); probable ATP-dependent RNA helicase DDX11; CHL1; CHL1 like helicase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX11-28322TH Recombinant Human DDX11, GST-tagged Wheat Germ GST
Human DDX11-11890H Recombinant Human DDX11, GST-tagged E.coli GST N-term-345a.a.
Human DDX11-454HCL Recombinant Human DDX11 cell lysate N/A
Mouse DDX11-4399M Recombinant Mouse DDX11 Protein Mammalian Cell His
Mouse DDX11-2263M Recombinant Mouse DDX11 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DDX11-2263M-B Recombinant Mouse DDX11 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DDX11-1711Z Recombinant Zebrafish DDX11 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DDX11 Related Research Area

DDX11 involved in several pathways and played different roles in them. We selected most pathways DDX11 participated on our site, such as IRE1alpha activates chaperones, Metabolism of proteins, Unfolded Protein Response (UPR), which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
IRE1alpha activates chaperonesADD1;WIPI1;HDGF;CXXC1;SERP1;CTDSP2;YIF1A;HYOU1;KLHDC3
Metabolism of proteinsARSF;NAT8;NSMCE1;ADAMTS20;PMPCB;CBX4;EXOC6;ADAMTS1;TMED10
Unfolded Protein Response (UPR)ASNA1;KDELR3;CXXC1;CTDSP2;YY2;PDIA6;KLHDC3;SERP1;WIPI1
XBP1(S) activates chaperone genesFKBP14;DNAJB9;KDELR3;KLHDC3;HYOU1;C19orf10;TPP1;YIF1A;SERP1

DDX11 has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding, ATP binding, ATP-dependent DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX11 itself. We selected most functions DDX11 had, and list some proteins which have the same functions with DDX11. You can find most of the proteins on our site.

Function Related Protein
4 iron, 4 sulfur cluster bindingACO1;NDUFV1;NUBP1;ISCA1;LIAS;NUBP2;NDUFS8;RSAD1;NTHL1
ATP bindingDCLK2;DARS2;MYHZ2;ATP8B1;UBE2G2;TNK2;CAMK2B;PIM1;CFTR
ATP-dependent DNA helicase activityG3BP1;GTF2H4;CHD1;DDX11;RTEL1;RUVBL2;ERCC3;XRCC5;FBXO18
DNA-dependent ATPase activityRAD51L3;SMARCA2;RAD51D;DHX36;RAD51L1;MSH4;ERCC2;DMC1;MSH3
RNA bindingNANOS1;HNRNPA2B1;NOM1;CNBPA;ZNF74;UBR5;YTHDC1;PRPF40B;FAM120A
double-stranded DNA bindingXRCC5;RAD51;FBXO18;EGFR;MEN1;MTERFD1;LSM14A;HMGB3;MRE11A
helicase activityMCM6L;SHPRH;WRN;TDRD12;HELZ;MCM3L;GTF2F2A;FANCM;SMARCA4
metal ion bindingZFP335;ZFP2;ZC3H10;ZNF831;PLA2G4D;MPPED2;F13A1;ACSM3;CYP2D10
protein bindingPHF21A;ADRB3;CUL4A;FBN1;TERF1;NME4;RAP1GAP;ZFP346;RDH12
single-stranded DNA bindingCNBP;TEN1;HNRNPK;SSBP3B;OBFC2B;RPA2;HMGB2;FUBP1;RAD51L1

DDX11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX11 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX11.

KAT7; PFN2

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All DDX11 Products

Required fields are marked with *

My Review for All DDX11 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends