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DDX21

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box helicase 21

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
  • Synonyms

    DDX21; DEAD (Asp-Glu-Ala-Asp) box helicase 21; DEAD (Asp Glu Ala Asp) box polypeptide 21 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 21; nucleolar RNA helicase 2; GURDB; RH II/GU; gu-alpha; Gu protein; DEAD box protein 21; RNA helicase II/Gu;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX21-11895H Recombinant Human DDX21, GST-tagged E.coli GST 1-180a.a.
Human DDX21-2474H Recombinant Human DDX21 Protein, GST-tagged Wheat Germ GST
Human DDX21-7015HCL Recombinant Human DDX21 293 Cell Lysate HEK293 N/A
Human DDX21-1615HFL Recombinant Full Length Human DDX21 Protein, C-Flag-tagged Mammalian cells Flag
Human DDX21-4431H Recombinant Human DDX21 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DDX21-741H Recombinant Human DDX21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DDX21-741H-B Recombinant Human DDX21 Protein Pre-coupled Magnetic Beads HEK293
Human DDX21-2902H Recombinant Human DDX21 protein, His-tagged E.coli His 620-783 aa
Human DDX21-2561HF Recombinant Full Length Human DDX21 Protein, GST-tagged In Vitro Cell Free System GST 783 amino acids
Mouse Ddx21-2502M Recombinant Mouse Ddx21 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DDX21-1817R Recombinant Rat DDX21 Protein Mammalian Cell His
Rat DDX21-1475R Recombinant Rat DDX21 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DDX21-1475R-B Recombinant Rat DDX21 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DDX21-6783Z Recombinant Zebrafish DDX21 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DDX21 involved in several pathways and played different roles in them. We selected most pathways DDX21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DDX21 has several biochemical functions, for example, 7SK snRNA binding, ATP binding, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX21 itself. We selected most functions DDX21 had, and list some proteins which have the same functions with DDX21. You can find most of the proteins on our site.

Function Related Protein
7SK snRNA bindingDDX21;HEXIM2;HEXIM1
ATP bindingCHUK;DYNC1LI2;cka1;POMK;SMC5;CSNK2A2;GKUP;NLRP5;UBE2H
ATP-dependent RNA helicase activityDDX39;DHX16;BAT1;DDX56;YTHDC2;EIF4A3;ACTG2;DHX9;DDX17
double-stranded RNA bindingELAVL1;OAS1A;EIF2C3;ZFP346;OAS1;APTX;TARBP2;MBNL1;CLTC
poly(A) RNA bindingMRPS14;NOC4L;EIF4E;MPHOSPH10;RPL10L;PRRC2A;RBM22;HNRNPA0;ALDH18A1
protein bindingOCRL;ATXN7;FOXG1;RRAGA;TNPO2;KLHL3;PKD2;CBLN3;SART3
rRNA bindingEMG1;RPS4X;ERI1;DDX21;RPS4Y2;TLR13;MRPS17;RPS4Y1;DIEXF
snoRNA bindingNUDT5;IMP4;HEATR1;NUDT16L1;UTP6;IMP3;NOP56;UTP15;TBL3

DDX21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX21 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX21.

YBX1; JUN; KPNA3; TERF2; SRPK2; ESR1; TOP1; RTCA; PSTPIP1

  • Q&As
  • Reviews

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Customer Reviews (3)

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Reviews
09/30/2022

    Benefiting from abundant experience and professional knowledge, the manufacturer offers unparalleled technical support and advice.

    04/30/2022

      The reasonable price of the reagent accommodates laboratory budget limitations.

      04/08/2017

        The reagent exhibits remarkable effectiveness, ensuring the accuracy and reliability of my experimental results.

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