Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

DDX3X

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
  • Synonyms

    ATP dependent RNA helicase DDX3X; DEAD box protein 3 X-chromosomal; DEAD box X isoform; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; HLP2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • Myc
  • His|B2M
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX3X-28325TH Recombinant Human DDX3X protein, GST-tagged Wheat Germ GST
Human DDX3X-257H Recombinant Human DDX3X protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DDX3X-7007HCL Recombinant Human DDX3X 293 Cell Lysate HEK293 N/A
Human DDX3X-2222H Recombinant Human DDX3X Protein (2-662 aa), His-B2M-tagged E.coli His/B2M 2-662 aa
Human DDX3X-1427HFL Recombinant Full Length Human DDX3X protein, Flag-tagged Mamanlian cells Flag
Human DDX3X-2214H Recombinant Human DDX3X protein, His&Myc-tagged Yeast His&Myc 2-662aa
Mouse Ddx3x-2506M Recombinant Mouse Ddx3x Protein, Myc/DDK-tagged HEK293T Myc/DDK
Chicken DDX3X-2498C Recombinant Chicken DDX3X Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DDX3X involved in several pathways and played different roles in them. We selected most pathways DDX3X participated on our site, such as Hepatitis B, RIG-I-like receptor signaling pathway, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX3X were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hepatitis BMAPK8;KRAS;TLR2;EGR3;BAD;BCL2;IFNA14;IFNA2;FADD
RIG-I-like receptor signaling pathwayPIN1;MAPK10;NFKBIB;TNF;IFNE;IFNA1;IKBKE;TP-1;NFKBIAB
TNF-alpha/NF-kB Signaling PathwayFAF1;TIFA;CAPN3;SMARCB1;TRAIP;KPNA6;PEG3;RNF25;COMMD1
Viral carcinogenesisHIST1H4E;RAC1;POLB;CCNE2;PMAIP1;GTF2H1;ACTN4;HLA-B;RHOA

DDX3X has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX3X itself. We selected most functions DDX3X had, and list some proteins which have the same functions with DDX3X. You can find most of the proteins on our site.

Function Related Protein
ATP bindingHSPA12A;RARS2;KDR;DHX58;HSPA1B;ACSL1;KCNJ1;HK3;OBSCN
ATP-dependent DNA helicase activityDHX9;BRIP1;CHD1;CHD4;XRCC6;BLM;ERCC2;DDX11;CHD2
ATP-dependent RNA helicase activitySKIV2L;DDX4;DDX28;DHX36;DDX5;DHX29;UPF1;DDX19B;PL10
ATPase activityDNAH5;RNF213;KIF2B;CHD1L;NSF;MYH9;ABCA13;KIF9;ABCA4
CTPase activity
DNA bindingSOS1;CREMB;KDM5D;POLR3F;ZFP473;PPARGC1A;TAF9;PREB;ZFAND3
GTPase activityRAB24;DNM2A;GNAI3;GBP3;RAB33A;RNF112;RAB25A;RAB3B;MSTO1
RNA bindingWT1;CPSF5;HDLBPA;NCL;RBM17;TRIM21;RPS14;TRDMT1;KHNYN
RNA stem-loop bindingEPRS;DAZAP1;CPEB3;DDX3X
eukaryotic initiation factor 4E bindingDDX3X;HHEX;EIF4EBP1;EIF4EBP3L;OTX2;EIF4EBP3;ANGEL1;GRA;EIF4G1
mRNA 5-UTR bindingDDX3X;IGF2BP1;LARP1;IGF2BP2;MRPS11;IGF2BP3;RPS14
nucleoside-triphosphatase activityENTPD8;DDX3X;NTPCR;ENTPD1;ENTPD6;ENTPD3
poly(A) RNA bindingHIST4H4;MBNL3;DDX6;CPSF4;HSPB1;PARN;CIRBP;HOXB6;TBL3
poly(A) bindingHNRNPDL;DDX3X;PABPC4;SYNCRIP;PABPN1;PAIP2B;KHDRBS2;KHDRBS1;TIA1
protein bindingBBC3;DNAJC10;TEAD4;OSR2;AQP5;MAGOH;IL1R2;STRN;ARL8A
ribosomal small subunit bindingNME1;MTIF3;CPEB2;DHX29;NPM1;PIM1;PTCD3;ERAL1;DDX3X
transcription factor bindingPIAS1;CSNK2B;FOXA1;FOXO1;NEUROD1;PPARGC1A;CEBPB;MYBBP1A;MECP2
translation initiation factor bindingLARP1;LIN28A;TRIM32;ZNF259;POLR2GL;CELF1;EIF2B5;POLR2G;EIF3M

DDX3X has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX3X here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX3X.

p27958-pro_0000037566; PABPC1

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All DDX3X Products

Required fields are marked with *

My Review for All DDX3X Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends