DDX4
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
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Overview
DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells. This enzyme is specific to germ cells and is necessary for germ cell development. Mouse DDX4 was shown to interact with Dicer suggesting a role in microRNA-medi -
Synonyms
DDX4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 4; probable ATP-dependent RNA helicase DDX4; VASA; vasa homolog; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- DDX4 Related Research Area
DDX4 involved in several pathways and played different roles in them. We selected most pathways DDX4 participated on our site, such as Gene Expression, Gene Silencing by RNA, PIWI-interacting RNA (piRNA) biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Gene Expression | ZNF658;ZNF354B;ZNF2;CHD4;SCO1;MBD3;RARAB;TUBB3;PLD6 |
Gene Silencing by RNA | TDRD1;PIWIL4;DGCR8;FKBP6;MYBL1;PLD6;TSNAX;EIF2C3;DPY19L2 |
PIWI-interacting RNA (piRNA) biogenesis | MYBL1;FKBP6;HENMT1;TDRD1;ASZ1;PLD6;PIWIL4;MAEL;DDX4 |
DDX4 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX4 itself. We selected most functions DDX4 had, and list some proteins which have the same functions with DDX4. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | TLK1A;VARS;ABCA8;PTK2B;NEK11;ROS1;ATP2B1;UBE2D3;PAK3 |
ATP-dependent RNA helicase activity | TDRD12;DHX16;DDX50;DHX33;DQX1;TMEM38A;DDX3;DDX49;DDX39A |
nucleic acid binding | RBPMS2;SSX1;ZFP629;ZSCAN4C;CL2;ZFP523;RBM4.2;ZBTB41;UMPS |
DDX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX4.
SRC; N; USE1
- Q&As
- Reviews
Q&As (5)
Ask a questionDDX4 protein expression is used as a biomarker for germ cell development and certain reproductive diseases, aiding in diagnosis and prognosis.
Yes, DDX4 protein plays an essential role in the development of both male and female gametes, making it a crucial factor in reproductive health.
DDX4 protein is involved in the regulation of oocyte and embryo development, and its dysregulation can impact fertility and reproductive outcomes.
DDX4 protein expression can be assessed using immunohistochemistry, western blotting, and other molecular techniques in clinical settings.
Yes, genetic mutations in DDX4 protein have been linked to certain forms of infertility and germ cell tumors.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
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