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DDX4

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 4

  • Overview

    DDX4 is an ATP-dependent DEAD-box RNA helicase found in the chromatoid body of the germ cells. This enzyme is specific to germ cells and is necessary for germ cell development. Mouse DDX4 was shown to interact with Dicer suggesting a role in microRNA-medi
  • Synonyms

    DDX4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 4; probable ATP-dependent RNA helicase DDX4; VASA; vasa homolog; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX4-11904H Recombinant Human DDX4, GST-tagged E.coli GST 35-198a.a.
Human DDX4-468H Recombinant Human DDX4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DDX4-2486H Recombinant Human DDX4 Protein, GST-tagged Wheat Germ GST
Human DDX4-7006HCL Recombinant Human DDX4 293 Cell Lysate HEK293 N/A
Human DDX4-2588HF Recombinant Full Length Human DDX4 Protein, GST-tagged In Vitro Cell Free System GST 690 amino acids
Human DDX4-743H-B Recombinant Human DDX4 Protein Pre-coupled Magnetic Beads HEK293
Human DDX4-2012H Recombinant Human DDX4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DDX4-2145H Recombinant Human DDX4 Protein (Asn35-Gly131), N-His tagged E.coli N-His Asn35-Gly131
Human DDX4-182H Recombinant Human DDX4 protein, His-tagged E. coli His 340-690 aa
Human DDX4-2675H Recombinant Human DDX4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DDX4-500HFL Recombinant Full Length Human DDX4 Protein, C-Flag-tagged Mammalian cells Flag
Human DDX4-743H Recombinant Human DDX4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ddx4-2507M Recombinant Mouse Ddx4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DDX4-1821R Recombinant Rat DDX4 Protein Mammalian Cell His
Rat DDX4-1479R-B Recombinant Rat DDX4 Protein Pre-coupled Magnetic Beads HEK293
Rat DDX4-1479R Recombinant Rat DDX4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey DDX4-457C Recombinant Cynomolgus DDX4 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey DDX4-203C Recombinant Cynomolgus Monkey DDX4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey DDX4-203C-B Recombinant Cynomolgus Monkey DDX4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DDX4-1218R Recombinant Rhesus monkey DDX4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DDX4-1043R Recombinant Rhesus Macaque DDX4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DDX4-1043R-B Recombinant Rhesus Macaque DDX4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DDX4-8685Z Recombinant Zebrafish DDX4 Mammalian Cell His
Chicken DDX4-6273C Recombinant Chicken DDX4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DDX4 Related Research Area

DDX4 involved in several pathways and played different roles in them. We selected most pathways DDX4 participated on our site, such as Gene Expression, Gene Silencing by RNA, PIWI-interacting RNA (piRNA) biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gene ExpressionZNF658;ZNF354B;ZNF2;CHD4;SCO1;MBD3;RARAB;TUBB3;PLD6
Gene Silencing by RNATDRD1;PIWIL4;DGCR8;FKBP6;MYBL1;PLD6;TSNAX;EIF2C3;DPY19L2
PIWI-interacting RNA (piRNA) biogenesisMYBL1;FKBP6;HENMT1;TDRD1;ASZ1;PLD6;PIWIL4;MAEL;DDX4

DDX4 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX4 itself. We selected most functions DDX4 had, and list some proteins which have the same functions with DDX4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTLK1A;VARS;ABCA8;PTK2B;NEK11;ROS1;ATP2B1;UBE2D3;PAK3
ATP-dependent RNA helicase activityTDRD12;DHX16;DDX50;DHX33;DQX1;TMEM38A;DDX3;DDX49;DDX39A
nucleic acid bindingRBPMS2;SSX1;ZFP629;ZSCAN4C;CL2;ZFP523;RBM4.2;ZBTB41;UMPS

DDX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX4.

SRC; N; USE1

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is DDX4 protein expression used in clinical diagnosis? 05/16/2020

DDX4 protein expression is used as a biomarker for germ cell development and certain reproductive diseases, aiding in diagnosis and prognosis.

Does DDX4 protein have a role in the development of male and female gametes? 10/17/2019

Yes, DDX4 protein plays an essential role in the development of both male and female gametes, making it a crucial factor in reproductive health.

How does DDX4 protein influence oocyte and embryo development? 01/11/2017

DDX4 protein is involved in the regulation of oocyte and embryo development, and its dysregulation can impact fertility and reproductive outcomes.

How is DDX4 protein expression assessed in clinical settings? 04/30/2016

DDX4 protein expression can be assessed using immunohistochemistry, western blotting, and other molecular techniques in clinical settings.

Are there any known genetic mutations affecting DDX4 protein associated with clinical conditions? 03/18/2016

Yes, genetic mutations in DDX4 protein have been linked to certain forms of infertility and germ cell tumors.

Customer Reviews (3)

Write a review
Reviews
08/19/2019

    Their prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.

    05/09/2018

      This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.

      10/24/2017

        Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.

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