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DDX42

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

  • Overview

    This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.
  • Synonyms

    DDX42; DEAD (Asp-Glu-Ala-Asp) box polypeptide 42; ATP-dependent RNA helicase DDX42; RHELP; RNAHP; SF3b125; DEAD box polypeptide 42 protein; DEAD box protein 42; EC 3.6.1.-; FLJ43179; RNA helicase-like protein; RNA helicase-related protein; SF3b DEAD-box protein; SF3b125 DEAD-box protein; Splicing factor 3B-associated 125 kDa protein; SF3b DEAD box protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX42-2490H Recombinant Human DDX42 Protein, GST-tagged Wheat Germ GST
Human DDX42-456HCL Recombinant Human DDX42 cell lysate N/A
Human DDX42-2604HF Recombinant Full Length Human DDX42 Protein, GST-tagged In Vitro Cell Free System GST 819 amino acids
Mouse DDX42-4419M Recombinant Mouse DDX42 Protein Mammalian Cell His
Mouse DDX42-2273M-B Recombinant Mouse DDX42 Protein Pre-coupled Magnetic Beads HEK293
Mouse DDX42-2273M Recombinant Mouse DDX42 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DDX42-1219R Recombinant Rhesus monkey DDX42 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DDX42-1044R Recombinant Rhesus Macaque DDX42 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DDX42-1044R-B Recombinant Rhesus Macaque DDX42 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DDX42-3601Z Recombinant Zebrafish DDX42 Mammalian Cell His
Chicken DDX42-2615C Recombinant Chicken DDX42 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DDX42 involved in several pathways and played different roles in them. We selected most pathways DDX42 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX42 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
SpliceosomeHNRNPC;BAT1;DDX5;THOC1;NHP2L1B;SFRS9;PLRG1;ALYREF;SF3B3

DDX42 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX42 itself. We selected most functions DDX42 had, and list some proteins which have the same functions with DDX42. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCDKL2;BMPR1B;MYO18A;ICK;BUB1B;AARS;AK3;ACTR1B;STK17A
ATP-dependent RNA helicase activityDHX32;DDX43;PL10;SKIV2L;DDX17;DDX55;DHX34;DDX27;DDX39AA
poly(A) RNA bindingEIF2S1A;PTCD1;DHX15;EIF1;RPL27;DHX16;RRP8;TOP2A;NXF2
protein bindingKATNBL1;KRTAP5-9;TRAM1;SCARB1;PHF17;WBP11;ATF6;BRMS1;WWP1

DDX42 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX42 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX42.

SF3A2; Sf3a1; U2SURP; DHX15; RECQL5; SNRPC; recX; SF3B4; SF3A1; anmK; PRPF19; Aff1; Kifc5b; Kif13b; ssrna_ug; Itgb1; VCAM1

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