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DDX50

  • Official Full Name

    DEAD (Asp-Glu-Ala-Asp) box polypeptide 50

  • Overview

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
  • Synonyms

    DDX50; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; ATP-dependent RNA helicase DDX50; GU2; GUB; MGC3199; RH II/GuB; 4933429B04Rik; DDX50_HUMAN; DEAD box protein 50; Gu beta; Gu-beta; MGC109605; Nucleolar protein Gu2; RH II; RNA helicase II / Gu beta; RNA helicase II/Gu beta; RH-II/GuB;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DDX50-2498H Recombinant Human DDX50 Protein, GST-tagged Wheat Germ GST
Human DDX50-469H Recombinant Human DDX50 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DDX50-28327TH Recombinant Human DDX50, His-tagged E.coli His
Human DDX50-7003HCL Recombinant Human DDX50 293 Cell Lysate HEK293 N/A
Human DDX50-2310H Recombinant Human DDX50 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DDX50-30159H Recombinant Human DDX50 protein, GST-tagged E.coli GST Glu136-VAL381
Human DDX50-2647HF Recombinant Full Length Human DDX50 Protein, GST-tagged In Vitro Cell Free System GST 737 amino acids
Mouse DDX50-4425M Recombinant Mouse DDX50 Protein Mammalian Cell His
Mouse DDX50-2276M Recombinant Mouse DDX50 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DDX50-2276M-B Recombinant Mouse DDX50 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DDX50-1222R Recombinant Rhesus monkey DDX50 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DDX50-1047R Recombinant Rhesus Macaque DDX50 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DDX50-1047R-B Recombinant Rhesus Macaque DDX50 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DDX50 involved in several pathways and played different roles in them. We selected most pathways DDX50 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DDX50 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX50 itself. We selected most functions DDX50 had, and list some proteins which have the same functions with DDX50. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPKN1;CAMKV;PSMC1B;DDX11;MYO6A;CLP1;AK7A;DNAH14;HSPA9
ATP-dependent RNA helicase activityDDX51;DDX23;CHST13;PL10;DDX39;DHX35;YTHDC2;DQX1;DDX59
poly(A) RNA bindingUTP18;RPL26L1;SCAF4;ARCN1;DDX49;RPL32;UTP15;SRP14;GTF2E2

DDX50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX50 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX50.

ESR2; SMNDC1; PINX1; KRAS; q81xs6_bacan; MED19; ssrna_ug; AIM2; MED26; ESR1; NPM1; RPL10; MNDA; HDGF; SRPK2; HNRNPU

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