DDX6
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Official Full Name
DEAD (Asp-Glu-Ala-Asp) box helicase 6
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Overview
The lymphoma-associated Rck/p54 gene product is a member of the DEAD box protein/RNA helicase family which has a variety of functions including translation initiation, pre-mRNA splicing, and ribosome assembly. Overexpression of human Rck in a guinea pig c -
Synonyms
DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; DEAD (Asp Glu Ala Asp) box polypeptide 6 , DEAD/H (Asp Glu Ala Asp/His) box polypeptide 6 (RNA helicase, 54kD) , HLR2; probable ATP-dependent RNA helicase DDX6; RCK; DEAD box-6; oncogene RCK; DEAD box protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | DDX6-28328TH | Recombinant Human DDX6 protein, GST-tagged | Wheat Germ | GST | ||
Human | DDX6-45H | Recombinant Human DDX6 protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | DDX6-6998HCL | Recombinant Human DDX6 293 Cell Lysate | HEK293 | N/A | ||
Human | DDX6-6899HF | Recombinant Full Length Human DDX6 Protein, GST-tagged | In Vitro Cell Free System | GST | 483 amino acids | |
Mouse | DDX6-4433M | Recombinant Mouse DDX6 Protein | Mammalian Cell | His | ||
Mouse | Ddx6-2515M | Recombinant Mouse Ddx6 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | DDX6-2280M | Recombinant Mouse DDX6 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | DDX6-2280M-B | Recombinant Mouse DDX6 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chicken | DDX6-5430C | Recombinant Chicken DDX6 | Mammalian Cell | His | ||
Chicken | DDX6-1464C | Recombinant Chicken DDX6 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- DDX6 Related Articles
DDX6 involved in several pathways and played different roles in them. We selected most pathways DDX6 participated on our site, such as Deadenylation-dependent mRNA decay, Gene Expression, RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DDX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Deadenylation-dependent mRNA decay | EIF4A2;EIF4EB;TNKS1BP1;EIF4G1;EIF4A1;DDX6;D1BWG0212E;DCP1B;EIF4B |
Gene Expression | CLP1;MANEA;GTF3AB;RARG;MBD3;ZNF200;SETB;ALKBH8;NR1I3 |
RNA degradation | PFKM;CNOT10;PABPC1;PAN3;PARN;LSM6;DCPS;LSM7;EXOSC5 |
mRNA decay by 5 to 3 exoribonuclease | DDX6;LSM6;DCP1B |
DDX6 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDX6 itself. We selected most functions DDX6 had, and list some proteins which have the same functions with DDX6. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | GSK3AA;BMPR1BB;DDX17;ABCD2;SETX;HLCS;LRRK1;FIGNL1;GUCY2E |
ATP-dependent RNA helicase activity | DDX39AA;DHX32;DHX16;DDX39A;EIF4A2;DHX9;DDX55;DDX19A;DDX43 |
RNA helicase activity | DHX15;SKIV2L2;FAM120B;DDX24;DDX5;DDX17;CTU1;CHST13;CCDC111 |
helicase activity | TDRD12;DHX57;DNA2;HELZ;HELLS;CHD9;CHD1L;DDX6;DDX52 |
poly(A) RNA binding | MRPS35;RRP7A;PEF1;SUB1;C11orf68;KCTD12;ARCN1;DYNC1H1;TMSB4X |
protein binding | Arid4b;TERF1;SERPINF1;SOX13;PLD2;PIGK;PLLP;ZBTB8A;PIBF1 |
protein domain specific binding | CACNB2;TFDP2;CRB3;CALM1;LIN7C;HGS;HIST1H4F;SP100;OCLN |
DDX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of DDX6.
DCP1A; EDC3; YBX1; TRIM37
- Q&As
- Reviews
Q&As (5)
Ask a questionThere is emerging interest in developing therapies that target DDX6 to modulate its activity, potentially impacting cancer cell growth.
Yes, DDX6 has been implicated in antiviral responses, influencing the replication of certain viruses.
DDX6 is a component of RNA granules and is involved in their assembly, influencing mRNA storage and translation repression.
DDX6 dysregulation has been observed in various cancers, suggesting its involvement in tumorigenesis and progression.
Some preclinical studies suggest the therapeutic potential of targeting DDX6, but clinical trials are still in the early stages.
Customer Reviews (3)
Write a reviewWhether it's troubleshooting experimental issues, providing guidance on experimental design, or answering any inquiries related to the DDX6 protein, the manufacturer is committed to helping researchers overcome challenges and achieve their scientific goals.
The manufacturer also values customer satisfaction and strives to maintain a strong relationship with researchers.
They actively seek feedback and incorporate it into their product development process, continuously improving the quality and performance of the DDX6 protein.
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