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DEDD

  • Official Full Name

    death effector domain containing

  • Overview

    This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    DEDD; death effector domain containing; death effector domain-containing protein; CASP8IP1; DEDD1; DEFT; FLDED1; KE05; Death effector domain containing protein; Death effector domain containing testicular molecule; DEDD 1; DEDPro 1; DEDPro1; FLDED 1; KE 05; OTTHUMP00000031822; FLDED-1; OTTHUMP00000031821; death effector domain-containing testicular molecule;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DEDD-539H Recombinant Human DEDD Protein, His-tagged E.coli His
Human DEDD-7245H Recombinant Human DEDD, His-tagged E.coli His 1-318aa
Human DEDD-538H Recombinant Human DEDD Protein, His-tagged E.coli His
Human DEDD-2513H Recombinant Human DEDD Protein, GST-tagged Wheat Germ GST
Human DEDD-6995HCL Recombinant Human DEDD 293 Cell Lysate HEK293 N/A
Human DEDD-6996HCL Recombinant Human DEDD 293 Cell Lysate HEK293 N/A
Human DEDD-2810H Recombinant Human DEDD protein, GST-tagged E.coli GST 1-318aa
Human DEDD-2416HF Recombinant Full Length Human DEDD Protein, GST-tagged In Vitro Cell Free System GST 318 amino acids
Rat DEDD-1827R Recombinant Rat DEDD Protein Mammalian Cell His
Rat DEDD-1485R-B Recombinant Rat DEDD Protein Pre-coupled Magnetic Beads HEK293
Rat DEDD-1485R Recombinant Rat DEDD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DEDD-1225R Recombinant Rhesus monkey DEDD Protein, His-tagged Mammalian Cell His
Rhesus Macaque DEDD-1050R-B Recombinant Rhesus Macaque DEDD Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DEDD-1050R Recombinant Rhesus Macaque DEDD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DEDD-750Z Recombinant Zebrafish DEDD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DEDD involved in several pathways and played different roles in them. We selected most pathways DEDD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DEDD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DEDD has several biochemical functions, for example, DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DEDD itself. We selected most functions DEDD had, and list some proteins which have the same functions with DEDD. You can find most of the proteins on our site.

Function Related Protein
DNA bindingRFX2;HMGB2B;SIM1A;ELF2B;KDM5B;ADNPA;MUS81;FOXJ1B;ZMAT2
protein bindingNPEPL1;CIRH1A;EIF2AK3;SH2D1B;RECQL;MAP1B;WAPAL;WTAP;FGF3

DEDD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DEDD here. Most of them are supplied by our site. Hope this information will be useful for your research of DEDD.

APLP2; C7orf28A; PAM; ARID4A; ATP6V1E1; KHK; SMAD3; TCEAL5; RSRC2; ABCA9; USP7; LTV1; SERPINI1; RANBP3; CCDC59; USP22; SHMT1; BATF2

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