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DENR

  • Official Full Name

    density-regulated protein

  • Overview

    This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.
  • Synonyms

    DENR; density-regulated protein; DRP; DRP1; SMAP 3; DENR_HUMAN; Density regulated protein; DRP1 protein; Protein DRP1; SMAP-3; SMAP3; Smooth muscle cell associated protein 3; Smooth muscle cell-associated protein 3; OTTHUMP00000239609; OTTHUMP00000239610; smooth muscle cell associated protein-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DENR-3643H Recombinant Human DENR, His-tagged Human His
Human DENR-2536H Recombinant Human DENR Protein, GST-tagged Wheat Germ GST
Human DENR-28065TH Recombinant Human DENR, His-tagged E.coli His
Human DENR-28066TH Recombinant Human DENR, His-tagged E.coli His 198 amino acids
Human DENR-6975HCL Recombinant Human DENR 293 Cell Lysate HEK293 N/A
Human DENR-2816H Recombinant Human DENR protein, His-SUMO-tagged E.coli His-SUMO 2-198aa
Human DENR-3927H Recombinant Human DENR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DENR-2466HF Recombinant Full Length Human DENR Protein, GST-tagged In Vitro Cell Free System GST 198 amino acids
Mouse DENR-4516M Recombinant Mouse DENR Protein Mammalian Cell His
Mouse DENR-2332M Recombinant Mouse DENR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Denr-2526M Recombinant Mouse Denr Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DENR-2332M-B Recombinant Mouse DENR Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DENR-800Z Recombinant Zebrafish DENR Mammalian Cell His
Chicken DENR-3544C Recombinant Chicken DENR Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DENR Related Articles

DENR involved in several pathways and played different roles in them. We selected most pathways DENR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DENR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DENR has several biochemical functions, for example, molecular_function, protein binding, translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DENR itself. We selected most functions DENR had, and list some proteins which have the same functions with DENR. You can find most of the proteins on our site.

Function Related Protein
molecular_functionCML3;RNFT1;FANCF;HIST1H2BA;CACFD1;ACTR5;TRIM6;FAM26E.1;MTMR11
protein bindingCOPE;PVRL1;GALNT3;MYOCD;CALCOCO2;TSSK1;PRLR;PLD3;CXorf40A
translation initiation factor activityEIF2S1A;EIF5;EIF1B;EIF4A1B;EIF3B;EIF4E3;MTIF2;EIF4A1A;EIF4G1

DENR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DENR here. Most of them are supplied by our site. Hope this information will be useful for your research of DENR.

UBC; MARCH5; MCTS1; NELFB; ACADVL

Chen, YJ; Shi, GY; et al. Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. CANCER RESEARCH 64:7302-7310(2004).
Xu, FP; Zhao, ZZJ; et al. Cell density regulates tyrosine phosphorylation and localization of focal adhesion kinase. EXPERIMENTAL CELL RESEARCH 262:49-58(2001).
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