DERL1
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Official Full Name
Der1-like domain family, member 1
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Overview
Derlin-1 also known as degradation in endoplasmic reticulum protein 1 is a protein that in humans is encoded by the DERL1 gene . It is a member of the rhomboid-like clan of polytopic membrane proteins. -
Synonyms
DERL1; Der1-like domain family, member 1; derlin-1; DER 1; DER1; derlin 1; FLJ13784; MGC3067; PRO2577; DERtrin-1; der1-like protein 1; degradation in endoplasmic reticulum protein 1; DER-1; FLJ42092;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Dictyostelium discoideum (Slime mold)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rhesus Macaque
- Zebrafish
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | DERL1-2546H | Recombinant Human DERL1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | DERL1-6971HCL | Recombinant Human DERL1 293 Cell Lysate | HEK293 | N/A | ||
Human | DERL1-2474HF | Recombinant Full Length Human DERL1 Protein, GST-tagged | In Vitro Cell Free System | GST | 251 amino acids | |
Mouse | DERL1-4523M | Recombinant Mouse DERL1 Protein | Mammalian Cell | His | ||
Mouse | DERL1-2336M-B | Recombinant Mouse DERL1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | DERL1-2336M | Recombinant Mouse DERL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Bos taurus (Bovine) | RFL11619BF | Recombinant Full Length Bovine Derlin-1(Derl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-251) | |
Dictyostelium discoideum (Slime mold) | RFL22195DF | Recombinant Full Length Dictyostelium Discoideum Probable Derlin-1 Homolog(Derl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-242) | |
Homo sapiens (Human) | RFL28598HF | Recombinant Full Length Human Derlin-1(Derl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-251) | |
Mus musculus (Mouse) | RFL7836MF | Recombinant Full Length Mouse Derlin-1(Derl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-251) | |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL9795PF | Recombinant Full Length Pongo Abelii Derlin-1(Derl1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-251) | |
Rhesus Macaque | DERL1-1244R | Recombinant Rhesus monkey DERL1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | DERL1-1069R | Recombinant Rhesus Macaque DERL1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | DERL1-1069R-B | Recombinant Rhesus Macaque DERL1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | DERL1-12615Z | Recombinant Zebrafish DERL1 | Mammalian Cell | His | ||
Chicken | DERL1-1494C | Recombinant Chicken DERL1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
DERL1 involved in several pathways and played different roles in them. We selected most pathways DERL1 participated on our site, such as Protein processing in endoplasmic reticulum, Amyotrophic lateral sclerosis (ALS), which may be useful for your reference. Also, other proteins which involved in the same pathway with DERL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein processing in endoplasmic reticulum | SEC24B;DNAJB2;UBE2D2A;UGGT1;SAR1A;TUSC3;SEL1L;MAPK8A;UBE2D1B |
Amyotrophic lateral sclerosis (ALS) | CASP12;MAP2K6;GRIN2B;BCL2L1;SLC1A2;CASP9;TNFRSF1A;DAXX;GRIN2D |
DERL1 has several biochemical functions, for example, ATPase binding, MHC class I protein binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DERL1 itself. We selected most functions DERL1 had, and list some proteins which have the same functions with DERL1. You can find most of the proteins on our site.
Function | Related Protein |
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ATPase binding | ATP1B2;RALB;METTL21A;DERL1;SLN;ATXN3;BBC3;DRD1;GRIN2A |
MHC class I protein binding | LILRB1;CD8A;PILRB2;CD8B;BCAP31;TUBB;TAPBP;CD244;DERL1 |
protease binding | TTN;ALPI;FADD;PEO1;FAP;SERPINB6;THAP5;TIMP4;SERPINA1 |
protein binding | CLTB;KRIT1;RCC1;FBP2;TNK2;TEC;CD9;FSTL3;DUSP23 |
receptor activity | NOTCH1A;RPA1;UBXN6;NCR3;NRXN1;ADIPOR2;LILRB2;CD2;NLGN4B |
ubiquitin protein ligase binding | TRAF1;UBE2N;ATP6V0C;CUL4B;ARRB1;TUBB;FAF1;HIF1A;VCP |
ubiquitin-specific protease binding | DERL1;CHMP3;PARK7;SART3;VCP;AMFR;SYVN1;PARK2;VPS24 |
DERL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DERL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DERL1.
TCF25; HM13; CFTR; BCAP31; VIMP; XBP1; ALB; US11; VCP
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