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DGKB

  • Official Full Name

    diacylglycerol kinase, beta 90kDa

  • Overview

    Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    DGKB; diacylglycerol kinase, beta 90kDa; DAGK2, diacylglycerol kinase, beta (90kD); diacylglycerol kinase beta; DGK; DGK BETA; KIAA0718; DAG kinase beta; diglyceride kinase beta; 90 kDa diacylglycerol kinase; DAGK2; DGK-BETA;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DGKB-11954H Recombinant Human DGKB, His-tagged E.coli His 30-140a.a.
Human DGKB-6958HCL Recombinant Human DGKB 293 Cell Lysate HEK293 N/A
Human DGKB-6959HCL Recombinant Human DGKB 293 Cell Lysate HEK293 N/A
Human DGKB-4338H Recombinant Human DGKB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse DGKB-4543M Recombinant Mouse DGKB Protein Mammalian Cell His
Mouse DGKB-2350M Recombinant Mouse DGKB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dgkb-2535M Recombinant Mouse Dgkb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DGKB-2350M-B Recombinant Mouse DGKB Protein Pre-coupled Magnetic Beads HEK293
Rat DGKB-1855R Recombinant Rat DGKB Protein Mammalian Cell His
Rat DGKB-1513R-B Recombinant Rat DGKB Protein Pre-coupled Magnetic Beads HEK293
Rat DGKB-1513R Recombinant Rat DGKB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DGKB Related Research Area

DGKB involved in several pathways and played different roles in them. We selected most pathways DGKB participated on our site, such as Choline metabolism in cancer, Effects of PIP2 hydrolysis, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGKB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Choline metabolism in cancerSLC22A5;KRAS;FOS;RHEB;WASL;SLC44A2;RAC3;GRB2;WASF1
Effects of PIP2 hydrolysisDGKA;TAE1;MGLL;DGKQ;DGKB;ABHD6B;TRPC6A;PRKCHB;RASGRP2
G alpha (q) signalling eventsRASGRP2;DGKQ;ARHGEF25;FFAR3;OPN4;UTS2D;HCRT;RGS19;FPR-RS3
GPCR downstream signalingTAS2R13;OPN5;OXGR1;PNOCB;TAS2R16;NPFF;CCL35.2;ARHGAP4A;GPR55
Gastrin-CREB signalling pathway via PKC and MAPKGRP;TRH;TAC2;DGKQ;HCRT;OPN4;GCGB;UTS2;MLN
Glycerolipid metabolismAKR1A1;ALDH1B1;CELL;LPL;PNLIPRP1;LIPF;ALDH2.2;ALDH3A2A;ALDH9A1A.1
Glycerophospholipid metabolismPLA2G3;PLA2G12B;GPD1A;DGKD;PLA2G4D;PLA2G2D;STIL;GPCPD1;TESCA
HemostasisANXA2;TAE1;SIRPA;DOCK7;ESAMA;AKAP1;NADL1.1;AKAP1B;KIF2A

DGKB has several biochemical functions, for example, ATP binding, calcium ion binding, diacylglycerol kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DGKB itself. We selected most functions DGKB had, and list some proteins which have the same functions with DGKB. You can find most of the proteins on our site.

Function Related Protein
ATP bindingUBA3;MARS2;FYNB;MAP3K10;DYNC1LI1;TTLL6;UBE2E2;KIF9;EIF4A1
calcium ion bindingANXA3B;PCDHGC4;S100S;FREM2;GM5077;FSTL5;PLCB4;CAPN3A;PLA2G12B
diacylglycerol kinase activityDGKG;DGKZ;DGKB;DGKA;DGKD;DGKE;AGK;DGKQ;TAE1

DGKB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGKB here. Most of them are supplied by our site. Hope this information will be useful for your research of DGKB.

KRT31; PCDHB5

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