DGKZ
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Official Full Name
diacylglycerol kinase, zeta
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Overview
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. -
Synonyms
DGKZ; diacylglycerol kinase, zeta; diacylglycerol kinase, zeta 104kDa; diacylglycerol kinase zeta; DAGK5; DAGK6; DGK ZETA; hDGKzeta; DAG kinase zeta; diglyceride kinase zeta; DGK-ZETA;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- DGKZ Related Articles
- DGKZ Related Research Area
DGKZ involved in several pathways and played different roles in them. We selected most pathways DGKZ participated on our site, such as Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGKZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glycerolipid metabolism | DGKAA;ALDH2.1;GLYCTK;ALDH9A1;MOGAT1;LIPG;AKR1B1L;ALDH7A1;PPAP2D |
Glycerophospholipid metabolism | CEPT1B;DGKZ;EPT1;AGPAT3;MBOAT2B;PLA2G5;PLA2G1B;PLA2G3;CHAT |
Metabolic pathways | G6PC;PPAP2A;ST6GALNAC1;GATC;CECR1A;CYP4A10;ITPKC;CKBB;AKR1B1 |
Phosphatidylinositol signaling system | PRKCA;CALML3;PIP4K2B;OCRL;PLCB4;PIK3C2B;PLCD1A;IPMKB;MTMR2 |
Phospholipase D signaling pathway | CXCR1;INS2;GRM1;MAPK3;PLCB2;PIK3R5;AKT2;LPAR4;PLA2G4F |
Choline metabolism in cancer | PIK3R2;PDPK1;RPS6KB1;WASL;CHKB;PLA2G4A;Pdgfa&Pdgfb;RAF1;SLC22A5 |
DGKZ has several biochemical functions, for example, ATP binding, diacylglycerol kinase activity, enzyme inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DGKZ itself. We selected most functions DGKZ had, and list some proteins which have the same functions with DGKZ. You can find most of the proteins on our site.
Function | Related Protein |
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ATP binding | PRPF4BA;RBKS;NEK3;DDX3;TBCK;RFK;CTPS2;CSNK1G3;TIE1 |
diacylglycerol kinase activity | TAE1;DGKD;DGKB;DGKZ;DGKAA;DGKG;DGKQ;AGK;DGKE |
enzyme inhibitor activity | SCG5;ATPIF1;APOV1;WFIKKN1;TXNIP;PRPSAP1;TAE1;APBA3;FRY |
lipid kinase activity | PIK3C2B;TAE1;DGKZ |
metal ion binding | DMRT2;KLF2A;NANOS1;ZFP583;POLK;TRIM35-21;ZNF592;KDM6B;TAX1BP1 |
protein C-terminus binding | HPCAL4;YEATS4;RAD51;CEP135;VPS36;MRE11A;XRCC5;CAV3;TFCP2 |
protein binding | ITGA3;CAV1;PDXP;Abcb1b;MED23;BRCC3;NUP50;YAP1;DAB2 |
DGKZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGKZ here. Most of them are supplied by our site. Hope this information will be useful for your research of DGKZ.
SAT1; MAPK6; GRINL1A; q8ckj5_yerpe; tnp_8; npm_alk; ARRB2; ARRB1; CBX8
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