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DHX36

  • Official Full Name

    DEAH (Asp-Glu-Ala-His) box polypeptide 36

  • Overview

    This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Synonyms

    DHX36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DDX36, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 36; probable ATP-dependent RNA helicase DHX36; KIAA1488; MLEL1; G4 resolvase-1; MLE-like protein 1; DEAH box protein 36; DEAD/H (Asp-Glu-Ala-Asp/His) bo;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DHX36-425HFL Recombinant Full Length Human DHX36 Protein, C-Flag-tagged Mammalian cells Flag
Human DHX36-1600H Recombinant Human DHX36 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DHX36-759H-B Recombinant Human DHX36 Protein Pre-coupled Magnetic Beads HEK293
Human DHX36-759H Recombinant Human DHX36 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DHX36-4579M Recombinant Mouse DHX36 Protein Mammalian Cell His
Mouse Dhx36-2560M Recombinant Mouse Dhx36 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DHX36-2367M Recombinant Mouse DHX36 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DHX36-2367M-B Recombinant Mouse DHX36 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DHX36 Related Articles

DHX36 involved in several pathways and played different roles in them. We selected most pathways DHX36 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX36 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationEXOSC7;DIS3;SKIV2L2;CNOT1;SMX5;EXOSC6;CNOT3A;DnaK;PFKP

DHX36 has several biochemical functions, for example, ATP binding, ATP-dependent RNA helicase activity, ATP-dependent helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX36 itself. We selected most functions DHX36 had, and list some proteins which have the same functions with DHX36. You can find most of the proteins on our site.

Function Related Protein
ATP bindingVARS;MCCC1;UBA1;RECQL5;MYHZ1.2;PIP4K2B;NEK10;ABCD4;CAMK2D
ATP-dependent RNA helicase activityDDX46;DHX30;DDX3X;DDX19B;ACTG2;DDX39B;DDX3Y;DDX5;DHX16
ATP-dependent helicase activityDHX36;TTF2;CHD4A;SNRNP200;DHX37;CHD6;BLM;RTEL1;ERCC6L2
DNA bindingELMSAN1A;ZNF484;CDK9;ZNF565;MYNN;FOXP2;TET3;HER4.2;MSGN1
DNA-dependent ATPase activityIGHMBP2;SMARCA2;XRCC2;TOP2A;RAD51L3;ERCC2;CHD6;CHD8;RAD51B
G-quadruplex DNA bindingLONP1;BLM;DHX36;WRN
G-quadruplex RNA bindingPATL2;Aff2;FXR1;DHX36
RNA bindingHNRPL;ELAVL1;KIAA0907;PES;ZNF385B;UMPS;DIMT1;NOVA1;PTBP1A
core promoter bindingHDAC1;HDAC4;NEUROG3;HMGA2;CLOCK;ELK1;ARNTL;MED1;E2F7
double-stranded RNA bindingOAS1A;LRRFIP1;MTDH;DROSHA;TLR3;OAS1;VIM;AGO2;AGO1
helicase activityYTHDC2;ATRX;DDX52;DQX1;TDRD12;EIF4A1B;GTF2F2;PL10;DDX6
histone deacetylase bindingSFPQ;MAGEA2B;CBX5;NIPBL;NKX2-5;BCOR;DHX36;HDAC6;WDTC1
hydrolase activityFIGNL1;GDPD4;SACM1LA;CAPN2A;PLAUB;DUSP19B;EXOSC9;ATP1A1A.3;TMPRSS11G
nucleic acid bindingGFI1AA;RNASE7;N6AMT2;SPAG7;ZNF711;SALL1A;RBM4B;INSM1B;ZBTB20
nucleotide bindingDPYDB;ABCG4B;CIRBPA;RAB5AA;SNRPA;KIF15;EPHB3A;TUBB5;REV3L
poly(A) RNA bindingPDCD11;MRPL15;NUDT21;TFAM;ZFP346;DHX16;PPIL4;RPL6;KIAA1967
protein bindingMAGEA11;MNDA;TMEM123;PHAX;ZNF625;GLP1R;TSC22D1;FAM46C;TSC2
transcription regulatory region DNA bindingIKZF1;TFE3;HIVEP3;HIVEP2;TCF7L2;GABPB2;TA;XRCC5;Arid4b

DHX36 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX36 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX36.

Hmga2; Ago2

Yoo, JS; Takahasi, K; et al. DHX36 Enhances RIG-I Signaling by Facilitating PKR-Mediated Antiviral Stress Granule Formation. PLOS PATHOGENS 10:-(2014).
Booy, EP; Howard, R; et al. The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. NUCLEIC ACIDS RESEARCH 42:3346-3361(2014).
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