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DHX9

  • Official Full Name

    DEAH (Asp-Glu-Ala-His) box polypeptide 9

  • Overview

    This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.
  • Synonyms

    DHX9; DEAH (Asp-Glu-Ala-His) box polypeptide 9; DDX9, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 9 (RNA helicase A, nuclear DNA helicase II; leukophysin) , LKP; ATP-dependent RNA helicase A; NDH II; RHA; leukophysin; DEAH box protein 9; nuclear DNA hel;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • Myc
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DHX9-32H Recombinant Human DHX9 protein, His/SUMO-tagged E.coli His/SUMO
Human DHX9-630H Recombinant Human DHX9 protein, Flag-Myc-tagged HEK293 Flag-Myc 325-840aa
Human DHX9-30765TH Recombinant Human DHX9 Wheat Germ N/A 90 amino acids
Human DHX9-631H Recombinant Human DHX9 protein, GST-tagged Wheat Germ GST 1 a.a. - 90 a.a.
Human DHX9-33H Recombinant Human DHX9 protein, His-tagged E.coli His 325-840aa
Human APOA1-699H Recombinant Human APOA1 protein E.coli N/A Arg19-Gln267
Mouse DHX9-4586M Recombinant Mouse DHX9 Protein Mammalian Cell His
Mouse Dhx9-3749M Recombinant Mouse Dhx9, His-tagged E.Coli or Yeast His 1383
Mouse DHX9-2372M Recombinant Mouse DHX9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DHX9-2372M-B Recombinant Mouse DHX9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DHX9-1264R Recombinant Rhesus monkey DHX9 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DHX9-1089R-B Recombinant Rhesus Macaque DHX9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DHX9-1089R Recombinant Rhesus Macaque DHX9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DHX9-7932Z Recombinant Zebrafish DHX9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DHX9 involved in several pathways and played different roles in them. We selected most pathways DHX9 participated on our site, such as Activated TLR4 signalling, Cytosolic sensors of pathogen-associated DNA, DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with DHX9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activated TLR4 signallingPELI2;DHX9;CHUK;DUSP3;TIRAP;NOD1;DUSP6;S100A12;TANK
Cytosolic sensors of pathogen-associated DNAALCAMB;AGER;TICAM1;MB21D1;APPB;NLRP4B;POLR3H;S100B;LRRFIP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines productionAGER;APPB;APPA;SAA1;ALCAMB;DHX9;CHST13;S100B;S100A12
Gene ExpressionGTF3AA;HNRPL;COX16;ZNF461;ZNF302;ZNF18;ZNF558;ZNF530;C2orf29
Immune SystemS100A12;ASB8;TNRC5;IFIT12;AP1M2;ERAP2;EDA;CXADR;ABI1A
Innate Immune SystemAGER;NLRP4;TXNIP;RCA2.1;IRAK3;WIPF2;DUSP3;BTR22;CFD
MyD88 cascade initiated on plasma membraneDHX9;S100B;TNIP2;PELI2;ALCAMB;TLR10;S100A12;PELI1;AGER
MyD88 dependent cascade initiated on endosomeCHST13;S100B;S100A12;ALCAMB;DHX9

DHX9 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DHX9 itself. We selected most functions DHX9 had, and list some proteins which have the same functions with DHX9. You can find most of the proteins on our site.

Function Related Protein
ATP bindingKCNJ11;UBE2T;STK38;QRSL1;ABCG5;MAP4K4;ABCC3;ACVR1L;INSRB
ATP-dependent DNA helicase activityGTF2H4;XRCC5;CHD2;BRIP1;BLM;CHST13;RECQL;WRN;CHD4
ATP-dependent RNA helicase activityDHX16;DDX49;DDX53;DDX39A;BAT1;DDX23;DDX27;ACTG2;DDX51
DNA bindingARID1AA;ZNF385A;SP5;ZNF266;POLG2;ZFAND5A;RPS15;FOXA;XRCC5
RNA helicase activityCHST13;DDX17;RAD54B;SKIV2L2;DHX16;DDX24;CCDC111;PRIM2;DDX5
RNA polymerase II transcription factor bindingDHX9;SFPI1;TEAD3;ATF4;ZFPM2;PITX2;GATA2A;TOX2;GATA4
poly(A) RNA bindingRPS5;FAM120A;POLR2B;MPHOSPH10;RPL17;CSTF3;SRSF9;UNK;NOL12
protein bindingSZL;AIM2;SETD6;Apba1;MOS;SYK;ADAMTS5;SEC23IP;FAM161A

DHX9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DHX9 here. Most of them are supplied by our site. Hope this information will be useful for your research of DHX9.

NXF1; YBX1; cte_mpmv

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