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DIAPH3

  • Official Full Name

    diaphanous homolog 3 (Drosophila)

  • Synonyms

    DIAPH3; diaphanous homolog 3 (Drosophila); auditory neuropathy, autosomal dominant 1 , AUNA1, diaphanous (Drosophila, homolog) 3; protein diaphanous homolog 3; AN; DRF3; FLJ34705; NSDAN; Dia2; diap3; DKFZp434C0931; DKFZp686A13178; RP11-26P21.1; DIAP3_HUMAN; Diaphanous homolog 3; Diaphanous related formin 3; Diaphanous-related formin-3; OTTHUMP00000018480; OTTHUMP00000180577; OTTHUMP00000180578; OTTHUMP00000180579; OTTHUMP00000180580; diaphanous-related formin 3; auditory neuropathy, autosomal dominant 1; AUNA1; mDia2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DIAPH3-2623H Recombinant Human DIAPH3 Protein, GST-tagged Wheat Germ GST
Human DIAPH3-1483H Recombinant Human DIAPH3 protein, His-tagged E.coli His 500 - 850 aa
Human DIAPH3-11993H Recombinant Human DIAPH3, GST-tagged E.coli GST C-term-350a.a.
Human DIAPH3-6924HCL Recombinant Human DIAPH3 293 Cell Lysate HEK293 N/A
Human DIAPH3-2558HF Recombinant Full Length Human DIAPH3 Protein, GST-tagged In Vitro Cell Free System GST 849 amino acids
Zebrafish DIAPH3-1049Z Recombinant Zebrafish DIAPH3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DIAPH3 Related Articles

DIAPH3 involved in several pathways and played different roles in them. We selected most pathways DIAPH3 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with DIAPH3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Regulation of actin cytoskeletonRRAS;LIMK1A;FGF13;ACTN1;PIP4K2C;APC;ITGAM;PPP1CB;PTK2AB

DIAPH3 has several biochemical functions, for example, Rho GTPase binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DIAPH3 itself. We selected most functions DIAPH3 had, and list some proteins which have the same functions with DIAPH3. You can find most of the proteins on our site.

Function Related Protein
Rho GTPase bindingDIAPH1;DIAPH3;ECT2;DAAM1;DIAP1;LRRK2;DOCK10;CDC42BPB;DOCK11
actin bindingHIP1;C19orf21;WIPF1A;TLN2A;TNS1;MYLK;TPM2;UPF3B;CAPZA1

DIAPH3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIAPH3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIAPH3.

Dlg4; MYC; SIRT1; SMAD9; PTBP3; SNW1

Schoen, CJ; Burmeister, M; et al. Diaphanous homolog 3 (Diap3) Overexpression Causes Progressive Hearing Loss and Inner Hair Cell Defects in a Transgenic Mouse Model of Human Deafness. PLOS ONE 8:-(2013).
Ji, P; Yeh, V; et al. Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 95:2013-2021(2010).
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