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DIRAS3

  • Official Full Name

    DIRAS family, GTP-binding RAS-like 3

  • Overview

    This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.
  • Synonyms

    DIRAS3; DIRAS family, GTP-binding RAS-like 3; ARHI, ras homolog gene family, member I; GTP-binding protein Di-Ras3; NOEY2; DIRA3; DIRA3_HUMAN; DIRAS family GTP binding RAS like 3; Distinct subgroup of the Ras family member 3; GTP binding protein Di Ras3; Rho related GTP binding protein RhoI; Rho-related GTP-binding protein RhoI; RHOI; ras homolog gene family, member I; ARHI;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • mFc
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DIRAS3-27416TH Recombinant Human DIRAS3, His-tagged E.coli His
Human DIRAS3-128H Recombinant Human DIRAS3, Fc tagged Human Cell His
Human DIRAS3-2638H Recombinant Human DIRAS3 Protein, GST-tagged Wheat Germ GST
Human DIRAS3-779HCL Recombinant Human DIRAS3 cell lysate Human Cell N/A
Human DIRAS3-2819H Recombinant Human DIRAS3 protein, GST-tagged E.coli GST 1-229aa
Human DIRAS3-4624H Recombinant Human DIRAS3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DIRAS3-2573HF Recombinant Full Length Human DIRAS3 Protein, GST-tagged In Vitro Cell Free System GST 229 amino acids
Human DIRAS3-764H Recombinant Human DIRAS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DIRAS3-292HFL Active Recombinant Full Length Human DIRAS3 Protein, C-Flag-tagged Mammalian cells Flag
Human DIRAS3-764H-B Recombinant Human DIRAS3 Protein Pre-coupled Magnetic Beads HEK293
Human DIRAS3-0267H Recombinant Human DIRAS3 protein, mFc-tagged HEK293 mFc Met1-Lys225
Rhesus Macaque DIRAS3-1269R Recombinant Rhesus monkey DIRAS3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DIRAS3-1094R Recombinant Rhesus Macaque DIRAS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DIRAS3-1094R-B Recombinant Rhesus Macaque DIRAS3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DIRAS3 involved in several pathways and played different roles in them. We selected most pathways DIRAS3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DIRAS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DIRAS3 has several biochemical functions, for example, GTP binding, GTPase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DIRAS3 itself. We selected most functions DIRAS3 had, and list some proteins which have the same functions with DIRAS3. You can find most of the proteins on our site.

Function Related Protein
GTP bindingRALBA;ARF4A;RAC1A;LGALS6;ADSSL1;GIMAP2;RHOG;MTIF2;GMPPAB
GTPase activityDIRAS1;GBP4;RRAS2;RAB36;RALBA;GNL3;GNGT2;EEF1A1L2;EEF2A.1
protein bindingSOSTDC1B;PTPN12;MEF2A;IKZF3;PRPF6;VAMP3;ZBTB43;VBP1;NOP58

DIRAS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIRAS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIRAS3.

STAT3; PPM1D; BAG4; CHEK2; KRAS; TGFB1; PTPN1; WT1; FGFR4; APC; PALB2; BRMS1

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