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DIS3L2

  • Official Full Name

    DIS3 mitotic control homolog (S. cerevisiae)-like 2

  • Synonyms

    DIS3L2; DIS3 mitotic control homolog (S. cerevisiae)-like 2; FAM6A, family with sequence similarity 6, member A; DIS3-like exonuclease 2; FLJ36974; MGC42174; DIS3 L2; DIS3 mitotic control homolog (S. cerevisiae) like 2; DIS3 mitotic control homolog like 2; family with sequence similarity 6, member A; FAM6A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DIS3L2-28352TH Recombinant Human DIS3L2, His-tagged E.coli His
Human DIS3L2-2641H Recombinant Human DIS3L2 Protein, GST-tagged Wheat Germ GST
Human DIS3L2-1103HCL Recombinant Human DIS3L2 cell lysate N/A
Human DIS3L2-2577HF Recombinant Full Length Human DIS3L2 Protein, GST-tagged In Vitro Cell Free System GST 619 amino acids
Human DIS3L2-2221H Recombinant Human DIS3L2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DIS3L2-1725HFL Recombinant Full Length Human DIS3L2 Protein, C-Flag-tagged Mammalian cells Flag
Human DIS3L2-301158H Recombinant Human DIS3L2 protein, GST-tagged E.coli GST Ala1-Ser170
Human DIS3L2-765H Recombinant Human DIS3L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DIS3L2-3773H Recombinant Human DIS3L2 protein, GST-tagged E.coli GST 99-201 aa
Human DIS3L2-765H-B Recombinant Human DIS3L2 Protein Pre-coupled Magnetic Beads HEK293
Human DIS3L2-1444H Recombinant Human DIS3L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse DIS3L2-4604M Recombinant Mouse DIS3L2 Protein Mammalian Cell His
Mouse DIS3L2-2385M Recombinant Mouse DIS3L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dis3l2-2570M Recombinant Mouse Dis3l2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DIS3L2-2385M-B Recombinant Mouse DIS3L2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DIS3L2 Related Articles

DIS3L2 involved in several pathways and played different roles in them. We selected most pathways DIS3L2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DIS3L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DIS3L2 has several biochemical functions, for example, 3-5-exoribonuclease activity, magnesium ion binding, poly(U) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DIS3L2 itself. We selected most functions DIS3L2 had, and list some proteins which have the same functions with DIS3L2. You can find most of the proteins on our site.

Function Related Protein
3-5-exoribonuclease activityDIS3L;ERI1;EXOSC2;ERI2;USB1;C16orf57;TOE1;EXOSC3;EXOSC4
magnesium ion bindingPPM1AA;ENOPH1;FIGNL1;PPA1B;SERPINB1A;OPA1;PRPSAP1;FARS2;LHPP
poly(U) RNA bindingPABPC1;HNRNPH1;PABPC4;MSI1;PATL1;DIS3L2;HNRNPC;KHDRBS1;MSI2
protein bindingRECQL4;MEMO1;ATP6V1E2;DCDC2B;SULT1A2;MCM4;ROCK1;APPL2;GRIK3
ribonuclease activityEAR1;RNASEL2;RNASET2;RNASEH2A;RSFR;RNASEL3;ANG;ANG4;DIS3L2

DIS3L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DIS3L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DIS3L2.

VIM; COPS6; FEZ1; ssdna_dn; CBX2; Wipi2; Mad2l1

Wegert, J; Ishaque, N; et al. Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors. CANCER CELL 27:298-311(2015).
Faehnle, CR; Walleshauser, J; et al. Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. NATURE 514:252-+(2014).
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