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DKK4

  • Official Full Name

    dickkopf homolog 4

  • Overview

    This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2.
  • Synonyms

    DKK4; dickkopf homolog 4 (Xenopus laevis); dickkopf (Xenopus laevis) homolog 4; dickkopf-related protein 4; hDkk-4; dickkopf-4; DKK-4; MGC129562; MGC129563;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DKK4-681H Active Recombinant Human DKK4 Protein, His-tagged Mammalian cells His Leu19-Leu224
Human DKK4-2668H Recombinant Human DKK4 Protein, GST-tagged Wheat Germ GST
Human DKK4-78H Recombinant Human DKK4, His-tagged HEK293 His
Human DKK4-6915HCL Recombinant Human DKK4 293 Cell Lysate HEK293 N/A
Human DKK4-1522H Recombinant Human DKK4 protein, His & T7-tagged E.coli His/T7 Gln107~His212 (Accession # Q9UBT3)
Human DKK4-3952HF Recombinant Full Length Human DKK4 Protein, GST-tagged In Vitro Cell Free System GST 224 amino acids
Human DKK4-2800H-B Recombinant Human DKK4 Protein Pre-coupled Magnetic Beads HEK293
Human DKK4-2800H Recombinant Human DKK4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DKK4-2085H Recombinant Human DKK4 Protein (Gln107-His212), N-His tagged E.coli N-His Gln107-His212
Mouse Dkk4-404M Active Recombinant Mouse Dickkopf Homolog 4 (Xenopus laevis), His-tagged Mammalian cells His
Mouse DKK4-4612M Recombinant Mouse DKK4 Protein Mammalian Cell His
Mouse Dkk4-2391M-B Recombinant Mouse Dkk4 Protein Pre-coupled Magnetic Beads HEK293
Mouse Dkk4-1523M Recombinant Mouse Dkk4 protein, His & GST-tagged E.coli His/GST Lys37~Glu141 (Accession # Q8VEJ3)
Mouse Dkk4-2391M Recombinant Mouse Dkk4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DKK4 Related Articles
  • DKK4 Related Research Area

DKK4 involved in several pathways and played different roles in them. We selected most pathways DKK4 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DKK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayROCK2A;TCF7L2;WNT10B;CUL1B;NFATC2;CAMK2D;WNT11B;CTNNBIP1;WNT6

DKK4 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DKK4 itself. We selected most functions DKK4 had, and list some proteins which have the same functions with DKK4. You can find most of the proteins on our site.

Function Related Protein
molecular_functionTMCC3;XRRA1;GM4305;XG;MXRA7;SMU1A;UBASH3BB;CFAP58;GM4220

DKK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DKK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DKK4.

Hong, FS; Hong, J; et al. Chronic Exposure to Nanoparticulate TiO2 Causes Renal Fibrosis Involving Activation of the Wnt Pathway in Mouse Kidney. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 63:1639-1647(2015).
Schon, S; Flierman, I; et al. beta-catenin regulates NF-kappa B activity via TNFRSF19 in colorectal cancer cells. INTERNATIONAL JOURNAL OF CANCER 135:1800-1811(2014).
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