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DLGAP1

  • Official Full Name

    discs, large homolog-associated protein 1

  • Overview

    Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP) is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post synaptic densityThis gene encodes the protein called guanylate kinase-associated protein (GKAP). GKAP binds to the SHANK and PSD-95 proteins fascilitating the assembly of the post synaptic density of neurons.Dlgap1 has five 14-amino acid repeats and three Pro-rich portions.
  • Synonyms

    DLGAP1; discs, large (Drosophila) homolog-associated protein 1; discs, large (Drosophila) homolog associated protein 1; disks large-associated protein 1; DAP 1; GKAP; SAPAP1; PSD-95/SAP90 binding protein 1; SAP90/PSD-95-associated protein 1; guanylate kin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DLGAP1-2680H Recombinant Human DLGAP1 Protein, GST-tagged Wheat Germ GST
Human DLGAP1-226HCL Recombinant Human DLGAP1 lysate HEK293 N/A
Human DLGAP1-3708H Recombinant Human DLGAP1 protein, GST-tagged E.coli GST 10 - 68 aa
Human DLGAP1-3868H Recombinant Human DLGAP1 protein, His-tagged E.coli His 10 - 68 aa
Rat DLGAP1-1882R Recombinant Rat DLGAP1 Protein Mammalian Cell His
Rat DLGAP1-1541R Recombinant Rat DLGAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DLGAP1-1541R-B Recombinant Rat DLGAP1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DLGAP1 Related Research Area

DLGAP1 involved in several pathways and played different roles in them. We selected most pathways DLGAP1 participated on our site, such as Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLGAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutamatergic synapseGNG12;PRKCB;TRPC1;GRIK4;SLC17A7;SLC38A1;ITPR3;SLC38A3;GRIA2

DLGAP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLGAP1 itself. We selected most functions DLGAP1 had, and list some proteins which have the same functions with DLGAP1. You can find most of the proteins on our site.

Function Related Protein
protein bindingMYL6;PRMT6;GNB1;FBP1;KIAA0101;EPM2A;ELL;NEDD8;PSMA4

DLGAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLGAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLGAP1.

GRB2; DLG4; Dlg1; ABL1; FYN; SRC; NCK1; PLCG1; PIK3R1; CRK

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