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DLX3

  • Official Full Name

    distal-less homeobox 3

  • Overview

    Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism.
  • Synonyms

    DLX3; distal-less homeobox 3; distal less homeo box 3; homeobox protein DLX-3; AI4; distal-less homeo box 3; DLX 3; DLX3_HUMAN; Homeobox protein DLX 3; TDO; OTTHUMP00000220808;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DLX3-26675TH Recombinant Human DLX3 Wheat Germ N/A 287 amino acids
Human DLX3-774H Recombinant Human DLX3 Protein, GST-His-tagged E.coli GST/His
Human DLX3-2482H Recombinant human DLX3, His-tagged E.coli His
Human DLX3-2693H Recombinant Human DLX3 Protein, GST-tagged Wheat Germ GST
Human DLX3-6906HCL Recombinant Human DLX3 293 Cell Lysate HEK293 N/A
Human DLX3-123HF Recombinant Full Length Human DLX3 Protein In Vitro Cell Free System 287 amino acids
Human DLX3-4004HF Recombinant Full Length Human DLX3 Protein, GST-tagged In Vitro Cell Free System GST 287 amino acids
Mouse DLX3-4636M Recombinant Mouse DLX3 Protein Mammalian Cell His
Mouse DLX3-2405M Recombinant Mouse DLX3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DLX3-2405M-B Recombinant Mouse DLX3 Protein Pre-coupled Magnetic Beads HEK293
Chicken DLX3-6367C Recombinant Chicken DLX3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DLX3 involved in several pathways and played different roles in them. We selected most pathways DLX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DLX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DLX3 has several biochemical functions, for example, chromatin binding, sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLX3 itself. We selected most functions DLX3 had, and list some proteins which have the same functions with DLX3. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingORC1L;JUN;DHX30;RBPJL;NKAP;SSRP1;BEND6;GATA6;ING2
sequence-specific DNA bindingTLX3B;IKZF1;MKX;SCAND2P;NFE2L2A;PKNOX1.1;RORCB;HLX1;EOMES
transcription factor activity, sequence-specific DNA bindingRB1;ZIC3;POU6F2;RFX5;SALL4;SIX3;CEBP1;ZNF35;BSX
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingNRF1;HOXA5;FOSB;RUNX2;SPI1;FOS;JUN;NFIA;NEUROD6

DLX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLX3.

TBL1X; TDP2

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