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DMBX1

  • Official Full Name

    diencephalon/mesencephalon homeobox 1

  • Overview

    This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    DMBX1; diencephalon/mesencephalon homeobox 1; orthodenticle homolog 3 (Drosophila) , OTX3; diencephalon/mesencephalon homeobox protein 1; PAXB; DMBX1_HUMAN; Homeoprotein MBX; Orthodenticle homolog 3 (Drosophila); Orthodenticle homolog 3; Paired-like homeobox protein DMBX1; Paired-like homeobox protein DMBX1-like; MBX; OTX3;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DMBX1-2701H Recombinant Human DMBX1 Protein, GST-tagged Wheat Germ GST
Human DMBX1-487HCL Recombinant Human DMBX1 cell lysate N/A
Human DMBX1-4012HF Recombinant Full Length Human DMBX1 Protein, GST-tagged In Vitro Cell Free System GST 377 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DMBX1 involved in several pathways and played different roles in them. We selected most pathways DMBX1 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DMBX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neural Crest DifferentiationDMBX1;ZIC1;GBX2;SOX5;OLIG1;HOXA1;CTBP2;TXLNB;OLIG2

DMBX1 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DMBX1 itself. We selected most functions DMBX1 had, and list some proteins which have the same functions with DMBX1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingRBFOX3;ZNF512;ETV5A;CHD8;FEZF1;ZFP536;ZFP553;HIST1H2BD;GM6026
RNA polymerase II regulatory region sequence-specific DNA bindingIKZF5;ATF2;RELA;GATA3;ZNF583;RORA;BARX1;IKZF3;ZFY1
protein heterodimerization activityPOLA1;HIST1H2BM;BCL2A1A;PBX1;SYCP3;PPP1CBL;CEBPB;ITGB1A;GTF2A1
protein homodimerization activityPITX2;S100A6;CRYBB2;BHLHB9;KCNK9;BCL2L10;GRM6;BCL2;KCNK3
sequence-specific DNA bindingHOXB4;ZNF35;POU3F2A;NR4A2A;TCF7L1A;RORCA;FOXQ1B;CREB5;FOXB1
transcription factor activity, sequence-specific DNA bindingCBL;MYCS;SFPI1;RB1;CNOT8;TEAD1A;HEY1;MSRB2;TCF3A
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific bindingBCL6AB;NR2F6;CDX2;E4F1;AEBP1;CGGBP1;MITF;MNT;ETV7

DMBX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DMBX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DMBX1.

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