DMD
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Official Full Name
dystrophin
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Overview
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. This complex is variously known as the costamere or the dystrophin-associated protein complex. Many muscle proteins, such as α-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with dystrophin at the costamere. -
Synonyms
DMD; dystrophin; BMD; CMD3B; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; OTTHUMP00000023117; OTTHUMP00000023121; OTTHUMP00000023124; OTTHUMP00000023125; OTTHUMP00000023126; OTTHUMP00000215590; OTTHUMP00000215591; OTTHUMP00000215592; OTTHUMP00000215846; Extracellular Signal-Regulated Kinase-1; ERK-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Human cells
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- DYKDDDDK
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | DMD-7053H | Recombinant Human DMD protein, His-tagged | E.coli | His | Ala3048~Ser3328 (Accession # P11532) | |
Human | DMD-13H | Recombinant Human DMD protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | DMD-12H | Recombinant Human DMD protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | DMD-2704H | Recombinant Human DMD Protein, GST-tagged | Wheat Germ | GST | ||
Human | DMD-26936TH | Recombinant Human DMD | Wheat Germ | N/A | 635 amino acids | |
Human | DMD-6899HCL | Recombinant Human DMD 293 Cell Lysate | HEK293 | N/A | ||
Human | DMD-9354HFL | Recombinant Full Length Human DMD protein, Flag-tagged | Mamanlian cells | Flag | ||
Human | DMD-4017HF | Recombinant Full Length Human DMD Protein, GST-tagged | In Vitro Cell Free System | GST | 635 amino acids | |
Human | DMD-2735H | Recombinant Human DMD Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | DMD-1972H | Recombinant Human DMD Protein (Ser3066-Ile3321), N-His tagged | E.coli | N-His | Ser3066-Ile3321 | |
Human | DMD-01H | Recombinant Human DMD Protein (Lys3200-Thr3684), N-His tagged | E.coli | N-His | Lys3200-Thr3684 | |
Human | DMD-36H | Recombinant Human DMD Protein, DYKDDDDK-tagged | Human cells | DYKDDDDK | ||
Human | DMD-37H | Recombinant Human DMD Protein, His-tagged | Human cells | His | ||
Human | DMD-1352H | Recombinant Human DMD Protein, His-tagged | E.coli | N-His | Ile253-Lys597 | |
Human | DMD-127HF | Recombinant Full Length Human DMD Protein | In Vitro Cell Free System | 635 amino acids | ||
Mouse | Dmd-7054M | Recombinant Mouse Dmd protein, His-tagged | E.coli | His | Ser3059~Ile3314 (Accession # P11531) | |
Mouse | DMD-4644M | Recombinant Mouse DMD Protein | Mammalian Cell | His | ||
Mouse | DMD-2410M | Recombinant Mouse DMD Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | DMD-2410M-B | Recombinant Mouse DMD Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | DMD-9299Z | Recombinant Zebrafish DMD | Mammalian Cell | His | ||
Chicken | DMD-6851C | Recombinant Chicken DMD | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- DMD Related Articles
DMD involved in several pathways and played different roles in them. We selected most pathways DMD participated on our site, such as Arrhythmogenic right ventricular cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, which may be useful for your reference. Also, other proteins which involved in the same pathway with DMD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Arrhythmogenic right ventricular cardiomyopathy | DAG1;DSG2;CDH2;CTNNA1;DSP;DSC2;DES;CTNNA2;CACNG2 |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) | DMD;SGCG;ITGA2B;CACNG6;DSG2;LMNA;DAG1;ITGA3;LEF1 |
Dilated cardiomyopathy | ITGA2B;ACTC1;ACTG1;LMNA;ITGA4;PRKACB;ITGA6;TPM4;ITGA8 |
Extracellular matrix organization | TLL2;COL8A1;LAMC3;COL10A1;ADAM15;NID1;LAMB1B;ADAM9;COL6A2 |
Hypertrophic cardiomyopathy (HCM) | MYL2;ITGA5;ACE;TGFB1;LAMA2;ITGA1;ITGB1;MYH7;TNNI3 |
Muscle contraction | SORBS3;TNNI2B.2;CMLC1;MYBPC3;MYL6B;TCAP;TMOD4;TNNI1;TMOD2 |
Non-integrin membrane-ECM interactions | LAMC3;DMD;TRAPPC4;TTR;DDR2;DDR1 |
Striated Muscle Contraction | VIML;SMYHC3;ACTA1B;MYBPC1;TNNT3B;TNNT1;MYBPC2A;TNNI2A.4;MYBPC2 |
DMD has several biochemical functions, for example, actin binding, dystroglycan binding, myosin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DMD itself. We selected most functions DMD had, and list some proteins which have the same functions with DMD. You can find most of the proteins on our site.
Function | Related Protein |
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actin binding | CAPZA1;HDAC6;LMOD2;MYH4;MYO1C;MYOT;DNASE1;MYO7A;SPTBN2 |
dystroglycan binding | AGR3;CLASP1;AGRN;AGR2;DAG1;MAP2;GYLTL1B;DMD;VCL |
myosin binding | CALD1B;VETZ;VAMP2;VEZT;USH2A;MYBPC3;RHOA;FXYD1;ARFGEF2 |
nitric-oxide synthase binding | SNTA1;DMD;DNM3;CD74;NOS1AP;ATP2B4;CAMK2D;ACTB;CAV1 |
protein binding | TUB;ILF2;UBE3A;STBD1;HIST1H4H;ASS1;MRPS31;RTF1;HAAO |
structural constituent of cytoskeleton | COX4I2;CYLC1;BICD1;KRT14;ADD3;ATXN1;SPTB;VIM;LOR |
structural constituent of muscle | PLEC;TPM1;TPM2;MYL6;MYL3;SORBS2;NEBL;DAG1;JPH1 |
vinculin binding | SORBS3;PXN;C22orf28;SYNM;DMD;DAG1;CTNNA1;TLN1;ACTN1 |
zinc ion binding | KDM5B;ZDHHC3B;ZMAT2;ABLIM2;CPZ;UHRF1;TRIM43;PHRF1;ADH4 |
DMD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DMD here. Most of them are supplied by our site. Hope this information will be useful for your research of DMD.
DTNB; DTNA; SNTB1; HAUS1; CTNNAL1; KRT19
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