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DNAJC24

  • Official Full Name

    DnaJ (Hsp40) homolog, subfamily C, member 24

  • Overview

    Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM;130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation;and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in;synthesis of diphthamide in EEF2 (Liu et al., 2004 (PubMed 15485916)).
  • Synonyms

    DNAJC24; DnaJ (Hsp40) homolog, subfamily C, member 24; DPH4, DPH4 homolog (JJJ3, S. cerevisiae) , DPH4, JJJ3 homolog (S. cerevisiae) , ZCSL3, zinc finger, CSL type containing 3; dnaJ homolog subfamily C member 24; JJJ3; 1700030A21Rik; DPH4, JJJ3 homolo;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DNAJC24-2758H Recombinant Human DNAJC24 Protein, GST-tagged Wheat Germ GST
Human DNAJC24-12081H Recombinant Human DNAJC24, GST-tagged E.coli GST 1-149a.a.
Human DNAJC24-7600H Recombinant Human DNAJC24, His-tagged E.coli N/A 1-149aa
Human DNAJC24-6874HCL Recombinant Human DNAJC24 293 Cell Lysate HEK293 N/A
Human DNAJC24-6289H Recombinant Human DNAJC24 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DNAJC24-4011HF Recombinant Full Length Human DNAJC24 Protein, GST-tagged In Vitro Cell Free System GST 148 amino acids
Mouse Dnajc24-2608M Recombinant Mouse Dnajc24 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque DNAJC24-1293R Recombinant Rhesus monkey DNAJC24 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DNAJC24-1118R Recombinant Rhesus Macaque DNAJC24 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DNAJC24-1118R-B Recombinant Rhesus Macaque DNAJC24 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DNAJC24-10756Z Recombinant Zebrafish DNAJC24 Mammalian Cell His
Chicken DNAJC24-4107C Recombinant Chicken DNAJC24 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DNAJC24 involved in several pathways and played different roles in them. We selected most pathways DNAJC24 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Metabolism of proteins, Post-translational protein modification, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJC24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activationDPH1;EEF2;ARSJ;PROZ;PROCA;OTOP2;EIF5A2;ARSD;ARSK
Metabolism of proteinsALG2;SFTPBB;GALNT6;PCSK2;VBP1;DNAJC19;FBXW2;PFDN1;B3GALTL
Post-translational protein modificationEID3;MLEC;ARSF;YKT6;SLC35A1;NSMCE4A;ADAMTSL3;CBX8;RNF2
Synthesis of diphthamide-EEF2DPH1;DPH5;DNAJC24;DPH2;WDR85;ATPBD4;DPH3;OTOP2

DNAJC24 has several biochemical functions, for example, ATPase activator activity, ferrous iron binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJC24 itself. We selected most functions DNAJC24 had, and list some proteins which have the same functions with DNAJC24. You can find most of the proteins on our site.

Function Related Protein
ATPase activator activityATP1B3;TOR1AIP1;ATP1B2;DNAJB6;ATP1B1;MYBPC3;DNAJC15;AHSA1L;RAB4A
ferrous iron bindingALKBH2;UROD;FXN;NT5E;ACP5;TRR1;TF;ALKBH1;DNAJC24
zinc ion bindingTCEA2;SYVN1;ADAMTS1;GTF2H2C_2;MMP20;ADAMTS15A;FANCL;LIMS2;ZCWPW1

DNAJC24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJC24 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJC24.

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