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DNALI1

  • Official Full Name

    dynein, axonemal, light intermediate chain 1

  • Overview

    This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
  • Synonyms

    DNALI1; dynein, axonemal, light intermediate chain 1; dynein, axonemal, light intermediate polypeptide 1; axonemal dynein light intermediate polypeptide 1; dJ423B22.5; dJ423B22.5 (axonemal dynein light chain (hp28)); hp28; inner dynein arm; homolog of clamydomonas; P28; Axonemal dynein light chain (hp28); Axonemal dynein light chain; DNALI 1; Dynein axonemal light intermediate chain 1; Dynein axonemal light intermediate polypeptide 1; Inner dynein arm homolog of clamydomonas; Inner dynein arm light chain axonemal; OTTHUMP00000004400; inner dynein arm light chain, axonemal; inner dynein arm, homolog of clamydomonas;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DNALI1-12093H Recombinant Human DNALI1, GST-tagged E.coli GST 1-258a.a.
Human DNALI1-3797H Recombinant Human DNALI1, His-tagged E.Coli or Yeast His 280
Human DNALI1-327H Recombinant Human dynein, axonemal, light intermediate chain 1, His-tagged E.coli His
Human DNALI1-2773H Recombinant Human DNALI1 Protein, GST-tagged Wheat Germ GST
Human DNALI1-499HCL Recombinant Human DNALI1 cell lysate N/A
Human DNALI1-2381H Recombinant Human DNALI1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DNALI1-2163H Recombinant Human DNALI1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DNALI1-4031HF Recombinant Full Length Human DNALI1 Protein, GST-tagged In Vitro Cell Free System GST 258 amino acids
Mouse Dnali1-2614M Recombinant Mouse Dnali1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DNALI1-1916R Recombinant Rat DNALI1 Protein Mammalian Cell His
Rat DNALI1-1575R Recombinant Rat DNALI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DNALI1-1575R-B Recombinant Rat DNALI1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey DNALI1-469C Recombinant Cynomolgus DNALI1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey DNALI1-215C Recombinant Cynomolgus Monkey DNALI1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey DNALI1-215C-B Recombinant Cynomolgus Monkey DNALI1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DNALI1-6110Z Recombinant Zebrafish DNALI1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DNALI1 involved in several pathways and played different roles in them. We selected most pathways DNALI1 participated on our site, such as Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNALI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Huntingtons diseaseNDUFB7;HIP1;NDUFA3;NDUFB1;POLR2I;PLCB4;EP300;NDUFB2;VDAC2

DNALI1 has several biochemical functions, for example, dynein heavy chain binding, microtubule motor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNALI1 itself. We selected most functions DNALI1 had, and list some proteins which have the same functions with DNALI1. You can find most of the proteins on our site.

Function Related Protein
dynein heavy chain bindingDNALI1;DYNC2LI1
microtubule motor activityKLC3;PROL1;KIF6;KIF2B;KLC1B;KIF20B;DNAIC2;KLC4;DNHD1
protein bindingMAGEH1;TMEM66;IL12B;PVRL3;IVL;TBX5;HFE2;TMEM74;RTN4RL2A

DNALI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNALI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNALI1.

SIAH1; HTT; PRMT6; EPS8; ABCF3; MED19; Med28; MED29

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