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DNMT3L

  • Official Full Name

    DNA (cytosine-5-)-methyltransferase 3-like

  • Overview

    DNMT 3L is a nuclear protein which has similarity to DNA methyltransferases, involved in de novo methylation of CpG islands.
  • Synonyms

    DNMT3L; DNA (cytosine-5-)-methyltransferase 3-like; DNA (cytosine-5)-methyltransferase 3-like; cytosine 5 methyltransferase 3 like protein; human cytosine 5 methyltransferase 3 like protein; MGC1090; cytosine-5-methyltransferase 3-like protein; human cyto;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DNMT3L-166H Active Recombinant Human DNMT3L, GST-tagged Sf9 Insect Cell GST
Human DNMT3L-26950TH Recombinant Human DNMT3L Wheat Germ N/A 100 amino acids
Human DNMT3L-203H Recombinant Human DNMT3L, His-tagged E.coli His 1-386aa
Human DNMT3L-6951H Recombinant Human DNMT3L, GST-tagged Sf9 Insect Cell GST Full length
Human DNMT3L-141H Recombinant Human DNMT3L, His-tagged E.coli His 1-387aa
Human DNMT3L-930H Recombinant Human DNMT3L Protein, DDK-tagged Sf9 Insect Cell DDK
Human DNMT3L-12111H Recombinant Human DNMT3L, His-tagged E.coli His 1-386a.a.
Human DNMT3L-2794H Recombinant Human DNMT3L Protein, GST-tagged Wheat Germ GST
Human DNMT3L-6852HCL Recombinant Human DNMT3L 293 Cell Lysate HEK293 N/A
Human DNMT3L-6853HCL Recombinant Human DNMT3L 293 Cell Lysate HEK293 N/A
Human DNMT3L-1897HFL Recombinant Full Length Human DNMT3L Protein, C-Flag-tagged Mammalian cells Flag
Human DNMT3L-4053HF Recombinant Full Length Human DNMT3L Protein, GST-tagged In Vitro Cell Free System GST 386 amino acids
Human DNMT3L-781H-B Recombinant Human DNMT3L Protein Pre-coupled Magnetic Beads HEK293
Human DNMT3L-781H Recombinant Human DNMT3L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dnmt3l-2623M Recombinant Mouse Dnmt3l Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DNMT3L-1927R Recombinant Rat DNMT3L Protein Mammalian Cell His
Rat DNMT3L-1586R Recombinant Rat DNMT3L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DNMT3L-1586R-B Recombinant Rat DNMT3L Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DNMT3L Related Research Area

DNMT3L involved in several pathways and played different roles in them. We selected most pathways DNMT3L participated on our site, such as DNA methylation, Epigenetic regulation of gene expression, Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNMT3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DNA methylationDNMT3L;DNMT1;UHRF1;DNMT3A;DNMT3B
Epigenetic regulation of gene expressionMTF2;SUZ12B;TAF1A;JARID2B;RRP8;SAP18;PHF19;DNMT3L;H3F3B.1
Gene ExpressionTRIM33;ZNF559;PIWIL4;PRDX2;TARBP2;ZNF671;POU2F1;POLR3C;MED13A
Trans-sulfuration and one carbon metabolismMTHFD2;DNMT3L

DNMT3L has several biochemical functions, for example, enzyme activator activity, enzyme binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNMT3L itself. We selected most functions DNMT3L had, and list some proteins which have the same functions with DNMT3L. You can find most of the proteins on our site.

Function Related Protein
enzyme activator activityALOX5AP;SAE1;CLPS;TAB1;TRIM23;ALDH1A2;OGT;MMP17;CASP9
enzyme bindingCAD;KRT79;RAC1;TSPAN17;LAMB1;UBE4B;DDC;TARBP2;ATP6AP2
metal ion bindingGPATCH8;CYP1C1;ZNF571;WDFY2;ZFP804A;ELOF1;ADAMTS7;POMT1;PCXB
protein bindingINTS4;ARMC8;NRADD;RARRES3;TMEM231;ACTL6A;JAKMIP1;HES1;EPB42

DNMT3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNMT3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DNMT3L.

RSL24D1; HDAC1; Dnmt3a; H3F3A; NUDT21; GSK3B; PHPT1

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