Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

DOHH

  • Official Full Name

    deoxyhypusine hydroxylase/monooxygenase

  • Overview

    This gene encodes a metalloenzyme that catalyzes the last step in the conversion of lysine to the unique amino acid hypusine in eukaryotic initiation factor 5A. The encoded protein hydroxylates deoxyhypusine to form hypusine in the mature eukaryotic initiation factor 5A protein. Alternative splicing results in multiple transcript variants.
  • Synonyms

    DOHH; deoxyhypusine hydroxylase/monooxygenase; HEAT like (PBS lyase) repeat containing 1 , HLRC1; deoxyhypusine hydroxylase; MGC4293; Deoxyhypusine dioxygenase; Deoxyhypusine monooxygenase; hDOHH; HEAT like PBS lyase repeat containing; HEAT like repeat containing protein 1; HEAT-like repeat-containing protein 1; HEAT-like (PBS lyase) repeat containing 1; HLRC1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DOHH-12125H Recombinant Human DOHH protein, His-tagged E.coli His 1-302 aa
Human DOHH-2809H Recombinant Human DOHH Protein, GST-tagged Wheat Germ GST
Human DOHH-505HCL Recombinant Human DOHH cell lysate N/A
Human DOHH-2480H Recombinant Human DOHH Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DOHH-6406H Recombinant Human DOHH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DOHH-1373H Recombinant Human DOHH Protein, His-tagged E.coli N-His Met1-Leu216
Human DOHH-3937HF Recombinant Full Length Human DOHH Protein, GST-tagged In Vitro Cell Free System GST 302 amino acids
Mouse DOHH-4760M Recombinant Mouse DOHH Protein Mammalian Cell His
Mouse DOHH-2482M Recombinant Mouse DOHH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dohh-201M Recombinant Mouse Dohh Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse DOHH-2482M-B Recombinant Mouse DOHH Protein Pre-coupled Magnetic Beads HEK293
Rat DOHH-1930R Recombinant Rat DOHH Protein Mammalian Cell His
Rat DOHH-1589R Recombinant Rat DOHH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Dohh-1374R Recombinant Rat Dohh Protein, His-tagged E.coli N-His Met1-Val210
Rat DOHH-1589R-B Recombinant Rat DOHH Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DOHH-1310R Recombinant Rhesus monkey DOHH Protein, His-tagged Mammalian Cell His
Rhesus Macaque DOHH-1135R Recombinant Rhesus Macaque DOHH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DOHH-1135R-B Recombinant Rhesus Macaque DOHH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DOHH-9966Z Recombinant Zebrafish DOHH Mammalian Cell His
Chicken DOHH-3064C Recombinant Chicken DOHH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DOHH Related Articles

DOHH involved in several pathways and played different roles in them. We selected most pathways DOHH participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Hypusine synthesis from eIF5A-lysine, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with DOHH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activationDHPS;DOHH;F9B;ARSK;DPH5;ARSH;DPH2;SUMF2;OTOP2
Hypusine synthesis from eIF5A-lysineEIF5A;DHPS;DOHH;EIF5A2
Metabolism of proteinsTRAPPC5;CCT7;CPA3;ST6GAL2B;TOMM40;IGFBP5A;SCFD1;SFTPC;KIFC3
Post-translational protein modificationNAPAB;ADAMTS13;TRAPPC6A;PPP6R1;ZNF408;MUC5AC;ALG10B;TFG;ADAMTSL4
hypusine biosynthesisDHPS;DOHH

DOHH has several biochemical functions, for example, deoxyhypusine monooxygenase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DOHH itself. We selected most functions DOHH had, and list some proteins which have the same functions with DOHH. You can find most of the proteins on our site.

Function Related Protein
deoxyhypusine monooxygenase activity
metal ion bindingPPP4CA;PDE11A;KITA;PRKCHA;NGB;TSNAX;ZNF614;CA4B;LHX2A
protein bindingMBNL1;CRTC2;KIAA0947;S100A8;ATXN7;PIH1D3;NLRC5;TSC22D3;MCRS1

DOHH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DOHH here. Most of them are supplied by our site. Hope this information will be useful for your research of DOHH.

ORF

Zappasodi, R; Bongarzone, I; et al. Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target. BLOOD 118:4421-4430(2011).
Sgier, D; Zuberbuehler, K; et al. Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA. PROTEIN ENGINEERING DESIGN & SELECTION 23:261-269(2010).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All DOHH Products

Required fields are marked with *

My Review for All DOHH Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends