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DPEP2

  • Official Full Name

    dipeptidase 2

  • Overview

    DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides,;including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed;during glutathione degradation (Habib et al., 2003 (PubMed 12738806)).
  • Synonyms

    DPEP2; dipeptidase 2; Dipeptidase2; DPEP 2; MBD 2; MBD2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • hFc
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DPEP2-8610H Recombinant Human DPEP2 protein(Met1-Ser376), hFc-tagged HEK293 C-hFc Met1-Ser376
Human DPEP2-8611H Recombinant Human DPEP2, His tagged Human Cell N/A
Human DPEP2-12137H Recombinant Human DPEP2, GST-tagged E.coli GST 32-379a.a.
Human DPEP2-2824H Recombinant Human DPEP2 Protein, GST-tagged Wheat Germ GST
Human DPEP2-1162HCL Recombinant Human DPEP2 cell lysate Human Cell N/A
Human DPEP2-1177HCL Recombinant Human DPEP2 cell lysate Human Cell N/A
Human DPEP2-208H Recombinant Human DPEP2 Protein, His-tagged E.coli His Leu303~Leu486
Human DPEP2-4009HF Recombinant Full Length Human DPEP2 Protein, GST-tagged In Vitro Cell Free System GST 399 amino acids
Human DPEP2-2350H Recombinant Human DPEP2 protein, His-tagged HEK293 His Met1-Ser376
Human DPEP2-2205H Recombinant Human DPEP2 Protein (Leu303-Leu486), His tagged E.coli His Leu303-Leu486
Mouse DPEP2-4780M Recombinant Mouse DPEP2 Protein Mammalian Cell His
Mouse DPEP2-2496M-B Recombinant Mouse DPEP2 Protein Pre-coupled Magnetic Beads HEK293
Mouse DPEP2-2496M Recombinant Mouse DPEP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DPEP2-1937R Recombinant Rat DPEP2 Protein Mammalian Cell His
Rat DPEP2-1596R Recombinant Rat DPEP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DPEP2-1596R-B Recombinant Rat DPEP2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DPEP2 Related Articles

DPEP2 involved in several pathways and played different roles in them. We selected most pathways DPEP2 participated on our site, such as Aflatoxin activation and detoxification, Arachidonic acid metabolism, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPEP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aflatoxin activation and detoxificationCYP2A13;PRKRA;CYP3A5;CYP1A2;GGT6;GGTLC1;ACY3.2;ACY3.1;ACY3
Arachidonic acid metabolismCBR1L;CYP2C9;ALOX8;GPX3;CYP2C19;CYP2P6;MAPKAPK2B;CYP2C39;CYP2AD2
Biological oxidationsCYP3A7;CYP2K19;GSTO2;FDX1L;SULT2ST2;CYP2N13;SULT1ST6;SLC35D1A;CYP8B2
MetabolismFTCD;BPNT1;CA5B;PPM1LB;CYP27B1;MMS19;ESRRA;GNG13B;BSG
Metabolism of lipids and lipoproteinsPTGR1;HSD17B11;APOEA;CYP24A1;INSIG2;Alb;ALOX5B.3;TIAM2;CYP27B1
Synthesis of Leukotrienes (LT) and Eoxins (EX)ALOX5B.3;DPEP2;PTGR1;DPEP1;ALOX5B.2;ALOX5AP
leukotriene biosynthesisDPEP1;DPEP2

DPEP2 has several biochemical functions, for example, dipeptidase activity, dipeptidyl-peptidase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPEP2 itself. We selected most functions DPEP2 had, and list some proteins which have the same functions with DPEP2. You can find most of the proteins on our site.

Function Related Protein
dipeptidase activityNAALAD2;NAALADL1;CNDP1;DPEP2;CNDP2;FOLH1;DPEP3;SCRN1;PEPD
dipeptidyl-peptidase activityDPP4;FAP;DPP8;DPP3;PRCP;DPEP1;DPP7;DPEP3;NAALAD2
metal ion bindingCNOT6;CYP2J6;MKRN4;LYAR;NUBP2;BCL6A;ZNF581;ZCCHC18;LIG4
metalloexopeptidase activityDPEP3;ERAP1;DPEP2;NUDT16;METAP1D;LAP3;NPEPL1;METAP2B;METAP2A

DPEP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPEP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPEP2.

uvrA

Sabra, A; Bessoule, JJ; et al. Host-Pathogen Interaction and Signaling Molecule Secretion Are Modified in the dpp3 Knockout Mutant of Candida lusitaniae. INFECTION AND IMMUNITY 82:413-422(2014).
Hast, BE; Goldfarb, D; et al. Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination. CANCER RESEARCH 73:2199-2210(2013).
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