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DPPA2

  • Official Full Name

    developmental pluripotency associated 2

  • Overview

    DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen—pointing to the presence of abnormal cell growth and the formation of cancerous cells.
  • Synonyms

    DPPA2; developmental pluripotency associated 2; developmental pluripotency-associated protein 2; developmental pluripotency-associated 2; embryonic stem cell-associated transcript 15-2 protein; pluripotent embryonic stem cell-related gene 1 protein; C80932; D19Mgi18; ECAT15-2; 2410088E07Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DPPA2-2852H Recombinant Human DPPA2 Protein, GST-tagged Wheat Germ GST
Human DPPA2-6827HCL Recombinant Human DPPA2 293 Cell Lysate HEK293 N/A
Human DPPA2-4149HF Recombinant Full Length Human DPPA2 Protein, GST-tagged In Vitro Cell Free System GST 298 amino acids
Rhesus Macaque DPPA2-1324R Recombinant Rhesus monkey DPPA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DPPA2-1149R-B Recombinant Rhesus Macaque DPPA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DPPA2-1149R Recombinant Rhesus Macaque DPPA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DPPA2 involved in several pathways and played different roles in them. We selected most pathways DPPA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DPPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DPPA2 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by DPPA2 itself. We selected most functions DPPA2 had, and list some proteins which have the same functions with DPPA2. You can find most of the proteins on our site.

Function Related Protein
molecular_functionCFAP126;PRL8A8;CCDC114;CMIP;IZUMO2;DEFB50;LIPN;MPDU1A;TUSC2B

DPPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPPA2.

DVL2; SPOP; PLOD3; ZNF250; U2AF2; FXR2; DPPA4; MCM10; ZCCHC10; DVL3; PBXIP1; MOAP1; AP2M1; SETD5; SDCBP2; VTA1

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