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DPYSL2

  • Official Full Name

    dihydropyrimidinase-like 2

  • Overview

    Collapsin Response Mediator Protein-2 (CRMP-2) is expressed at high levels in the developing nervous system and plays a critical role in axonal outgrowth by specifying axon/dendrite fate and establishing neuronal polarity. CRMP-2 enhances axon elongation
  • Synonyms

    DPYSL2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; CRMP2; DHPRP2; DRP 2; DRP2; unc-33-like phosphoprotein 2; collapsin response mediator protein hCRMP-2; N2A3; DRP-2; ULIP2; CRMP-2; ULIP-2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DPYSL2-101H Recombinant Human DPYSL2, GST-tagged Wheat Germ GST
Human DPYSL2-1193H Recombinant Human DPYSL2 Protein, His-tagged Yeast His
Human DPYSL2-102H Recombinant Human DPYSL2, GST-tagged Wheat Germ GST
Human DPYSL2-3908H Recombinant Human DPYSL2 protein, His-tagged E.coli His 224-572 aa
Human DPYSL2-6907HF Recombinant Full Length Human DPYSL2 Protein, GST-tagged In Vitro Cell Free System GST 572 amino acids
Human DPYSL2-787H Recombinant Human DPYSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DPYSL2-2539H Recombinant Human DPYSL2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DPYSL2-787H-B Recombinant Human DPYSL2 Protein Pre-coupled Magnetic Beads HEK293
Human DPYSL2-6183H Recombinant Human DPYSL2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DPYSL2-1988H Recombinant Human DPYSL2 Protein (Thr13-Glu490), N-His tagged E.coli N-His Thr13-Glu490
Human DPYSL2-42HFL Active Recombinant Full Length Human DPYSL2 Protein, C-Flag-tagged Mammalian cells Flag
Mouse DPYSL2-4812M Recombinant Mouse DPYSL2 Protein Mammalian Cell His
Mouse DPYSL2-2520M Recombinant Mouse DPYSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dpysl2-2651M Recombinant Mouse Dpysl2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DPYSL2-2520M-B Recombinant Mouse DPYSL2 Protein Pre-coupled Magnetic Beads HEK293
Rat DPYSL2-1949R Recombinant Rat DPYSL2 Protein Mammalian Cell His
Rat DPYSL2-1608R Recombinant Rat DPYSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DPYSL2-1608R-B Recombinant Rat DPYSL2 Protein Pre-coupled Magnetic Beads HEK293
Chicken DPYSL2-6064C Recombinant Chicken DPYSL2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DPYSL2 Related Articles

DPYSL2 involved in several pathways and played different roles in them. We selected most pathways DPYSL2 participated on our site, such as Axon guidance, BDNF signaling pathway, CRMPs in Sema3A signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPYSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceNFATC4;SLIT1;SEMA4C;NRTN;ANK2B;ABL1;PPP3CA;SRGAP3;CSK
BDNF signaling pathwaySYN1;EIF4EBP1;BCL2L11;KCNN2;GRIP1;CSNK2A1;CSNK2A1P;EIF2S1;LINGO1
CRMPs in Sema3A signalingSEMA3A;CDK5;DPYSL4;SEMA3AA;DPYSL2;CRMP1;NRP1A;CDK5R1B;DPYSL5B
Developmental BiologyEFNA3B;EFNB2;MED20;EFNA2A;EFNA5;DPYSL5B;AP2S1;TCF3A;EPHA2
L1CAM interactionsANK2B;SCN8A;DPYSL2;NRP1A;NRP2;SCN3B;DLG3;KIF4A;SCN9A
Recycling pathway of L1EZRA;DPYSL2;NADL1.1;DPYSL2B
Regulation of Microtubule CytoskeletonCFL2;MARK1;TPPP;MAP1B;TESK2;MARK2;DPYSL2
Semaphorin interactionsCDK5R1B;PLXND1;SEMA3AB;NRP1A;DPYSL3;SEMA4D;CRMP1;DPYSL2B;SEMA3AA

DPYSL2 has several biochemical functions, for example, dihydropyrimidinase activity, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPYSL2 itself. We selected most functions DPYSL2 had, and list some proteins which have the same functions with DPYSL2. You can find most of the proteins on our site.

Function Related Protein
dihydropyrimidinase activityDPYSL2;DPYS
microtubule bindingKIF18B;FTCD;PEX14;MAP205;MAP2;APC2;MAP6D1;CLIP3;KIF13B
protein bindingTLN1;SERBP1;SPINK7;PAX3;SOCS3;ANGPT1;CSTF2;MAP4K4;OTUB1
protein kinase bindingNPM1;MAP3K13;ARHGEF7;PTK2;H2AFY;MAVS;TELO2;SYN1;AP2A2

DPYSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPYSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPYSL2.

DPYSL3; DPYSL3; DPYSL5; GORASP2; MICALL1; GRK1; DPYSL4

Tan, F; Wahdan-Alaswad, R; et al. Dihydropyrimidinase-like protein 3 expression is negatively regulated by MYCN and associated with clinical outcome in neuroblastoma. CANCER SCIENCE 104:1586-1592(2013).
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