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DPYSL5

  • Official Full Name

    dihydropyrimidinase-like 5

  • Overview

    This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified.
  • Synonyms

    DPYSL5; dihydropyrimidinase-like 5; dihydropyrimidinase-related protein 5; CRAM; CRMP 5; CRMP5; Ulip6; DRP-5; ULIP-6; CRMP3-associated molecule; UNC33-like phosphoprotein 6; collapsin response mediator protein 5; collapsin response mediator protein-5; CRMP-5; FLJ45383;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DPYSL5-2868H Recombinant Human DPYSL5 Protein, GST-tagged Wheat Germ GST
Human DPYSL5-12160H Recombinant Human DPYSL5, GST-tagged E.coli GST 265-564
Human DPYSL5-1276H Recombinant Human DPYSL5 protein, His-tagged E.coli His Met1~Ala205
Human DPYSL5-509HCL Recombinant Human DPYSL5 cell lysate N/A
Human DPYSL5-2537H Recombinant Human DPYSL5 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DPYSL5-4747H Recombinant Human DPYSL5 protein, His&Myc-tagged E.coli His&Myc 1-564aa
Human DPYSL5-1721H Recombinant Human DPYSL5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DPYSL5-4174HF Recombinant Full Length Human DPYSL5 Protein, GST-tagged In Vitro Cell Free System GST 564 amino acids
Human DPYSL5-291HFL Recombinant Full Length Human DPYSL5 Protein, C-Flag-tagged Mammalian cells Flag
Human DPYSL5-790H Recombinant Human DPYSL5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DPYSL5-790H-B Recombinant Human DPYSL5 Protein Pre-coupled Magnetic Beads HEK293
Mouse DPYSL5-4815M Recombinant Mouse DPYSL5 Protein Mammalian Cell His
Mouse DPYSL5-2521M Recombinant Mouse DPYSL5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dpysl5-2654M Recombinant Mouse Dpysl5 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DPYSL5-2521M-B Recombinant Mouse DPYSL5 Protein Pre-coupled Magnetic Beads HEK293
Rat DPYSL5-1951R Recombinant Rat DPYSL5 Protein Mammalian Cell His
Rat DPYSL5-1610R Recombinant Rat DPYSL5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DPYSL5-1610R-B Recombinant Rat DPYSL5 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DPYSL5 Related Articles

DPYSL5 involved in several pathways and played different roles in them. We selected most pathways DPYSL5 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DPYSL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceCLTB;RND1L;EPHA5;EFNA2;COL6A3;RGS3;PAK1;SDCBP;EPHB1

DPYSL5 has several biochemical functions, for example, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, microtubule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DPYSL5 itself. We selected most functions DPYSL5 had, and list some proteins which have the same functions with DPYSL5. You can find most of the proteins on our site.

Function Related Protein
hydrolase activity, acting on carbon-nitrogen (but not peptide) bondsDPYSL5A;DPYSL2B;YDJC;CRMP1;BTD;NAAA;DPYSL5;DPYSL4;DPYSL3
microtubule bindingKIF3CB;AKAP1;MAPRE1A;KIF5B;GOLGA2;WDR43;SKA1;PRNP;CAMSAP1
protein bindingSUV39H1;AP1M1;ACVR2B;RARS;PAWR;SNAP23;FGF7;DHDDS;SERPINB8

DPYSL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPYSL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPYSL5.

DPYSL2; HSPA5; DARS2; APPL1

Akane, H; Shiraki, A; et al. Glycidol induces axonopathy and aberrations of hippocampal neurogenesis affecting late-stage differentiation by exposure to rats in a framework of 28-day toxicity study. TOXICOLOGY LETTERS 224:424-432(2014).
Manivannan, J; Tay, SSW; et al. DIHYDROPYRIMIDINASE-LIKE 3 REGULATES THE INFLAMMATORY RESPONSE OF ACTIVATED MICROGLIA. NEUROSCIENCE 253:40-54(2013).
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