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DRAM1

  • Official Full Name

    DNA-damage regulated autophagy modulator 1

  • Overview

    This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
  • Synonyms

    DRAM1; DNA-damage regulated autophagy modulator 1; DNA damage-regulated autophagy modulator protein 1; damage regulated autophagy modulator; DRAM; FLJ11259; damage-regulated autophagy modulator;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rhesus Macaque
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DRAM1-235HCL Recombinant Human DRAM1 lysate HEK293 N/A
Mouse DRAM1-4818M Recombinant Mouse DRAM1 Protein Mammalian Cell His
Mouse DRAM1-2524M Recombinant Mouse DRAM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DRAM1-2524M-B Recombinant Mouse DRAM1 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL34791HF Recombinant Full Length Human Dna Damage-Regulated Autophagy Modulator Protein 1(Dram1) Protein, His-Tagged E.coli expression system His Full Length (1-238)
Mus musculus (Mouse) RFL20432MF Recombinant Full Length Mouse Dna Damage-Regulated Autophagy Modulator Protein 1(Dram1) Protein, His-Tagged E.coli expression system His Full Length (1-238)
Rhesus Macaque DRAM1-1327R Recombinant Rhesus monkey DRAM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DRAM1-1152R Recombinant Rhesus Macaque DRAM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DRAM1-1152R-B Recombinant Rhesus Macaque DRAM1 Protein Pre-coupled Magnetic Beads HEK293
Xenopus laevis (African clawed frog) RFL29312XF Recombinant Full Length Xenopus Laevis Dna Damage-Regulated Autophagy Modulator Protein 1(Dram1) Protein, His-Tagged E.coli expression system His Full Length (1-239)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL505XF Recombinant Full Length Xenopus Tropicalis Dna Damage-Regulated Autophagy Modulator Protein 1(Dram1) Protein, His-Tagged E.coli expression system His Full Length (1-239)
Zebrafish DRAM1-1563Z Recombinant Zebrafish DRAM1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DRAM1 Related Articles

DRAM1 involved in several pathways and played different roles in them. We selected most pathways DRAM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DRAM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DRAM1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DRAM1 itself. We selected most functions DRAM1 had, and list some proteins which have the same functions with DRAM1. You can find most of the proteins on our site.

Function Related Protein
protein bindingMON2;AURKA;HNRNPD;SOX17;PTCH1;CD86;ANKRA2;RYR1B;PYCRL

DRAM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DRAM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DRAM1.

C1orf21

Guan, JJ; Zhang, XD; et al. DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX. CELL DEATH & DISEASE 6:-(2015).
Yu, MQ; Jiang, YG; et al. DRAM1 Protects Neuroblastoma Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Injury via Autophagy. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:19253-19264(2014).
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