DRD5
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Official Full Name
dopamine receptor D5
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Overview
This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. This receptor is neuron specific, localized primarily within limbic regions of the brain. Defects in DRD5 are a cause of blepharospasm and may be a cause of schizophrenia. -
Synonyms
DRD5; dopamine receptor D5; DBDR; DRD1B; DRD1L2; MGC10601; D(1B) dopamine receptor; OTTHUMP00000158603; dopamine D5 receptor; dopamine receptor D1B; d(5) dopamine receptor; D1beta dopamine receptor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Homo sapiens (Human)
- Human
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Xenopus laevis (African clawed frog)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- DRD5 Related Articles
- DRD5 Related Research Area
DRD5 involved in several pathways and played different roles in them. We selected most pathways DRD5 participated on our site, such as Amine ligand-binding receptors, Calcium signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with DRD5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Amine ligand-binding receptors | HRH3;DRD4;ADRA2B;CHRM5;DRD1;ADRA1D;DRD3;ADRA2A;ADRB3 |
Calcium signaling pathway | ADORA2AB;ADRa1A;ITPKB;P2RX8;GRPR;ORAI1;TRHR2;TNNC1B;MYLK2 |
Class A/1 (Rhodopsin-like receptors) | FPR-RS6;OXGR1A.2;CHRM1;GPR37B;DRD2;CCK;APLNR;NMU;CCL35.2 |
Dopamine receptors | DRD3;DRD2;DRD1;DRD5;DRD4 |
Dopaminergic synapse | SLC18A1;KCNJ5;PPP2R1B;PPP2R5A;ARNTL;KCNJ3;ATF4;CREB3;PRKCG |
G alpha (s) signalling events | NPS;ADRB3;ADORA2B;PTHRP2;CALCB;RLN3;PTH2;ADM2A;RAMP3 |
GPCR downstream signaling | SSTR2;GPR55;OR10A5;SCT;FPR-RS3;CCL19A.2;TIAM2;FPR-RS4;TRPC7 |
GPCR ligand binding | APLNR;CHRM1;LPAR2A;CRHR2;GPBAR1;OXGR1A.2;ADCYAP1B;RCA2.1;OPN4 |
DRD5 has several biochemical functions, for example, G-protein coupled amine receptor activity, dopamine binding, dopamine neurotransmitter receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DRD5 itself. We selected most functions DRD5 had, and list some proteins which have the same functions with DRD5. You can find most of the proteins on our site.
Function | Related Protein |
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G-protein coupled amine receptor activity | TAAR7B;TAAR6;DRD1A;GPR161;TAAR8C;DRD4B;DRD1;TAAR8B;TAAR7F |
dopamine binding | DRD1;SLC6A3;TH;DRD2B;DRD3;DRD2;DRD2L;DRD4;DRD1A |
dopamine neurotransmitter receptor activity | DRD1B;DRD2A;DRD5;DRD4-RS;DRD4B;DRD2B;DRD1;DRD7;DRD4 |
dopamine neurotransmitter receptor activity, coupled via Gs | DRD5;DRD1B;DRD1;DRD1A |
DRD5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DRD5 here. Most of them are supplied by our site. Hope this information will be useful for your research of DRD5.
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