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DSCAM

  • Official Full Name

    Down syndrome cell adhesion molecule

  • Overview

    The Dscam family of cell surface proteins mediates recognition events between neurons that play an essential role in the establishment of neural circuits in many organisms. Interneurons form synaptic connections with retinal ganglion cells in specific layers. Dscam and DscamL are expressed in different subsets of interneurons and ganglion cells. Interestingly, interneurons and ganglion cells that target to the same layer, express the same Dscam protein.
  • Synonyms

    DSCAM; Down syndrome cell adhesion molecule; Down syndrome cell adhesion molecule homolog; 4932410A21Rik;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DSCAM-1000H Active Recombinant Human DSCAM Mammalian cells N/A Glu18-Met1595
Human DSCAM-2882H Recombinant Human DSCAM Protein, GST-tagged Wheat Germ GST
Human DSCAM-12170H Recombinant Human DSCAM, His-tagged E.coli His C-term-100a.a.
Human DSCAM-4388H-B Recombinant Human DSCAM Protein Pre-coupled Magnetic Beads HEK293
Human DSCAM-4388H Recombinant Human DSCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DSCAM-4834M Recombinant Mouse DSCAM Protein Mammalian Cell His
Mouse DSCAM-2535M Recombinant Mouse DSCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DSCAM-2535M-B Recombinant Mouse DSCAM Protein Pre-coupled Magnetic Beads HEK293
Rat DSCAM-1961R Recombinant Rat DSCAM Protein Mammalian Cell His
Rat DSCAM-1620R-B Recombinant Rat DSCAM Protein Pre-coupled Magnetic Beads HEK293
Rat DSCAM-1620R Recombinant Rat DSCAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DSCAM Related Articles
  • DSCAM Related Research Area

DSCAM involved in several pathways and played different roles in them. We selected most pathways DSCAM participated on our site, such as Cell-Cell communication, DSCAM interactions, FOXA1 transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSCAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell-Cell communicationKIRREL3L;PLEC;CDH13;CLDN4;CDH5;SPTBN1;CDH4;ANG;JUPA
DSCAM interactionsDSCAML1;DSCAM;DCC;DSCAMA
FOXA1 transcription factor networkNFIA;DSCAM;AP1B1;CC10;NRIP1;TFF1;NFIB;FOXA1;CYP2C18

DSCAM has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSCAM itself. We selected most functions DSCAM had, and list some proteins which have the same functions with DSCAM. You can find most of the proteins on our site.

Function Related Protein
protein bindingEIF3M;TRPC5;XPO7;ATP6V0A4;TUBB;THY1;SYT1;NUDCD2;ARSA

DSCAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSCAM here. Most of them are supplied by our site. Hope this information will be useful for your research of DSCAM.

Ng, TH; Chiang, YA; et al. Review of Dscam-mediated immunity in shrimp and other arthropods (Reprinted from Dev Comp Immunol, vol 46, pg 129-138, 2014). DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 48:306-314(2015).
Ng, TH; Chiang, YA; et al. Review of Dscam-mediated immunity in shrimp and other arthropods. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 46:129-138(2014).
  • Q&As
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