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DTNBP1

  • Official Full Name

    dystrobrevin binding protein 1

  • Overview

    The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation.
  • Synonyms

    DTNBP1; dystrobrevin binding protein 1; sdy; Bloc1s8; AW048963; dysbindin; 5430437B18Rik; dysbindin; sandy; dysbindin-1; BLOC-1 subunit 8; HPS7 protein homolog; dystrobrevin-binding protein 1; hermansky-Pudlak syndrome 7 protein homolog; biogenesis of lysosome-related organelles complex 1 subunit 8;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DTNBP1-26457TH Recombinant Human DTNBP1, His-tagged E.coli His
Human DTNBP1-308H Recombinant Human Dystrobrevin Binding Protein 1 E.coli His
Human DTNBP1-26932TH Recombinant Human DTNBP1, His-tagged E.coli His
Human DTNBP1-2902H Recombinant Human DTNBP1 Protein, GST-tagged Wheat Germ GST
Human DTNBP1-6796HCL Recombinant Human DTNBP1 293 Cell Lysate HEK293 N/A
Human DTNBP1-4063HF Recombinant Full Length Human DTNBP1 Protein, GST-tagged In Vitro Cell Free System GST 351 amino acids
Human DTNBP1-2303H Recombinant Human DTNBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DTNBP1-2233H Recombinant Human DTNBP1 Protein (Gln100-Ser351), N-His tagged E.coli N-His Gln100-Ser351
Mouse DTNBP1-4853M Recombinant Mouse DTNBP1 Protein Mammalian Cell His
Mouse Dtnbp1-682M Recombinant Mouse Dtnbp1 Protein, His-tagged E.coli His Gln179~Glu319
Mouse DTNBP1-2546M-B Recombinant Mouse DTNBP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse DTNBP1-2546M Recombinant Mouse DTNBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dtnbp1-2672M Recombinant Mouse Dtnbp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DTNBP1-1966R Recombinant Rat DTNBP1 Protein Mammalian Cell His
Rat DTNBP1-1625R-B Recombinant Rat DTNBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat DTNBP1-1625R Recombinant Rat DTNBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Dtnbp1-683R Recombinant Rat Dtnbp1 Protein, His-tagged E.coli His Asp110~Leu305
Chicken DTNBP1-1515C Recombinant Chicken DTNBP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DTNBP1 involved in several pathways and played different roles in them. We selected most pathways DTNBP1 participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTNBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Clathrin derived vesicle buddingCLVS1;SNX9A;DTNBP1;SNX9;PICALMB;DNM2;AP1S3A;DTNBP1B;TBC1D8B
Golgi Associated Vesicle BiogenesisTFR1B;AP4B1;FTH1A;PUM1;AP1G1;AP3S1;YIPF6;AP1M2;HIP1R
Membrane TraffickingARCN1B;CX30.3;PUM1;ANKRD28;TRAPPC4;CLVS2;TFR1B;PICALMB;NECAP1
Vesicle-mediated transportCLINT1;PPP6R3;SH3D19;TFR1B;MYO6A;ARCN1B;CX30.3;TRAPPC9;STAB2
trans-Golgi Network Vesicle BuddingFTH1B;YIPF6;CLINT1;SNAPIN;GAK;SNX9A;NECAP1;DTNBP1B;AP4B1

DTNBP1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTNBP1 itself. We selected most functions DTNBP1 had, and list some proteins which have the same functions with DTNBP1. You can find most of the proteins on our site.

Function Related Protein
protein bindingRAD17;CDC25B;GTF2E2;CISH;FAM124A;PHF16;HYAL3;SRGN;ZNF695

DTNBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTNBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTNBP1.

SNAPIN; BLOC1S2; BLOC1S5; BLOC1S6; BLOC1S1

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