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DTX1

  • Official Full Name

    deltex homolog 1 (Drosophila)

  • Overview

    Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.
  • Synonyms

    DTX1; deltex homolog 1 (Drosophila); protein deltex-1; hDx 1; Deltex protein 1; Deltex-1; Deltex1; FXI-T1; Fxit 1; Fxit1; mDTX1; hDTX1; OTTHUMP00000241684; hDx-1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DTX1-2905H Recombinant Human DTX1 Protein, GST-tagged Wheat Germ GST
Human DTX1-1842H Recombinant Human DTX1 protein, His & T7-tagged E.coli His/T7 Gly290~His535 (Accession # Q86Y01)
Human DTX1-4067HF Recombinant Full Length Human DTX1 Protein, GST-tagged In Vitro Cell Free System GST 620 amino acids
Mouse DTX1-4856M Recombinant Mouse DTX1 Protein Mammalian Cell His
Mouse DTX1-2548M Recombinant Mouse DTX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DTX1-2548M-B Recombinant Mouse DTX1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DTX1-6779Z Recombinant Zebrafish DTX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DTX1 Related Articles
  • DTX1 Related Research Area

DTX1 involved in several pathways and played different roles in them. We selected most pathways DTX1 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Notch signaling pathwayMFAP5;NOTCH4;CIR1;NOTCH2;NOTCH1B;DLC;MYCBP;CTBP2A;MIB1

DTX1 has several biochemical functions, for example, Notch binding, SH3 domain binding, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX1 itself. We selected most functions DTX1 had, and list some proteins which have the same functions with DTX1. You can find most of the proteins on our site.

Function Related Protein
Notch bindingNOTCH1;SNW1;NOV;JAG2;JAG1A;ADAM17;JAG2B;AAK1;GALNT11
SH3 domain bindingMVB12A;DTX1;NCF1;SKAP1;EVLB;RAD9;SH3BP5;SGIP1;ITM2B
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activitySHRPRBCK1R;G2E3;RNF180;RNF149;TRIM41;TRIM71;RNF169;RFWD2;ITCHA
coenzyme F420-0 gamma-glutamyl ligase activityMUL1A;RC3H2;MARCH4;RNF180;RFWD2;RNF144AA;SHRPRBCK1R;SIAH1A;UBE2IA
coenzyme F420-2 alpha-glutamyl ligase activityRNF187;SIAH1A;HERC2;TMEM129;MYLIPA;RNF149;MARCH4;MARCH6;RFWD2
ligase activityTRIM5;BARD1;TRIM68;TRIM23;NEURL3;UBE2G1B;ZNRF2;TRIM39;RNF115
metal ion bindingTRIM36;THAP4;GIT1;DTD1;SDHD;ZNF69;FDX1B;EIF2S2;GNAT2
protein bindingLOXL2;LDB3;FAM109A;TSPYL4;PRKACA;CDK7;TLE3;TULP1;STRAP
protein-glutamic acid ligase activityRNF169;NEURL1B;MYLIPA;SIAH2L;ITCHA;MARCH6;TMEM129;MARCH5L;TRIM50
protein-glycine ligase activitySIAH1A;RNF187;RNF144AB;MARCH4;ARIH1L;NEURL3;NEURL1B;DTX1;MARCH9
protein-glycine ligase activity, elongatingRFWD2;MYLIPB;MUL1A;RAG1;ARIH1L;DTX1;TRIM50;MARCH5L;SIAH2L
protein-glycine ligase activity, initiatingDTX1;G2E3;TRIM50;UBE2IA;MARCH6;TRIM41;MUL1A;RFWD2;RNF144AA
ribosomal S6-glutamic acid ligase activityHERC2;TRIM50;SHRPRBCK1R;RNF149;UBE2M;RAG1;MARCH5L;ZNRF2B;ITCHA
tubulin-glutamic acid ligase activityMYLIPB;RFWD2;RAG1;RNF169;TTLL1;LTN1;NEURL1B;ZNRF3;MARCH11
tubulin-glycine ligase activityITCHA;HECW2;RFWD2;RAG1;MARCH11;RNF144AA;MARCH5L;UBR1;G2E3
ubiquitin protein ligase bindingCUL3A;HIF1A;UBE2NB;SMAD3;PRDX6;RRAGA;SUMO2;UBE2G1;CHEK2
zinc ion bindingDYTN;JHDM1D;TRIM43A;BTR18;MEP1B;ZNRF2;TRIM2A;RFPL4;TRIM35-34

DTX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX1.

Aste-Amezaga, M; Zhang, NY; et al. Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors. PLOS ONE 5:-(2010).
Laycock, MV; Jellett, JF; et al. First report of a new rapid assay for diarrhetic shellfish poisoning toxins. HARMFUL ALGAE 5:74-78(2006).
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