DTX1
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Official Full Name
deltex homolog 1 (Drosophila)
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Overview
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. -
Synonyms
DTX1; deltex homolog 1 (Drosophila); protein deltex-1; hDx 1; Deltex protein 1; Deltex-1; Deltex1; FXI-T1; Fxit 1; Fxit1; mDTX1; hDTX1; OTTHUMP00000241684; hDx-1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | DTX1-2905H | Recombinant Human DTX1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | DTX1-1842H | Recombinant Human DTX1 protein, His & T7-tagged | E.coli | His/T7 | Gly290~His535 (Accession # Q86Y01) | |
Human | DTX1-4067HF | Recombinant Full Length Human DTX1 Protein, GST-tagged | In Vitro Cell Free System | GST | 620 amino acids | |
Mouse | DTX1-4856M | Recombinant Mouse DTX1 Protein | Mammalian Cell | His | ||
Mouse | DTX1-2548M | Recombinant Mouse DTX1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | DTX1-2548M-B | Recombinant Mouse DTX1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | DTX1-6779Z | Recombinant Zebrafish DTX1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- DTX1 Related Articles
- DTX1 Related Research Area
DTX1 involved in several pathways and played different roles in them. We selected most pathways DTX1 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Notch signaling pathway | MFAP5;NOTCH4;CIR1;NOTCH2;NOTCH1B;DLC;MYCBP;CTBP2A;MIB1 |
DTX1 has several biochemical functions, for example, Notch binding, SH3 domain binding, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX1 itself. We selected most functions DTX1 had, and list some proteins which have the same functions with DTX1. You can find most of the proteins on our site.
Function | Related Protein |
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Notch binding | NOTCH1;SNW1;NOV;JAG2;JAG1A;ADAM17;JAG2B;AAK1;GALNT11 |
SH3 domain binding | MVB12A;DTX1;NCF1;SKAP1;EVLB;RAD9;SH3BP5;SGIP1;ITM2B |
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | SHRPRBCK1R;G2E3;RNF180;RNF149;TRIM41;TRIM71;RNF169;RFWD2;ITCHA |
coenzyme F420-0 gamma-glutamyl ligase activity | MUL1A;RC3H2;MARCH4;RNF180;RFWD2;RNF144AA;SHRPRBCK1R;SIAH1A;UBE2IA |
coenzyme F420-2 alpha-glutamyl ligase activity | RNF187;SIAH1A;HERC2;TMEM129;MYLIPA;RNF149;MARCH4;MARCH6;RFWD2 |
ligase activity | TRIM5;BARD1;TRIM68;TRIM23;NEURL3;UBE2G1B;ZNRF2;TRIM39;RNF115 |
metal ion binding | TRIM36;THAP4;GIT1;DTD1;SDHD;ZNF69;FDX1B;EIF2S2;GNAT2 |
protein binding | LOXL2;LDB3;FAM109A;TSPYL4;PRKACA;CDK7;TLE3;TULP1;STRAP |
protein-glutamic acid ligase activity | RNF169;NEURL1B;MYLIPA;SIAH2L;ITCHA;MARCH6;TMEM129;MARCH5L;TRIM50 |
protein-glycine ligase activity | SIAH1A;RNF187;RNF144AB;MARCH4;ARIH1L;NEURL3;NEURL1B;DTX1;MARCH9 |
protein-glycine ligase activity, elongating | RFWD2;MYLIPB;MUL1A;RAG1;ARIH1L;DTX1;TRIM50;MARCH5L;SIAH2L |
protein-glycine ligase activity, initiating | DTX1;G2E3;TRIM50;UBE2IA;MARCH6;TRIM41;MUL1A;RFWD2;RNF144AA |
ribosomal S6-glutamic acid ligase activity | HERC2;TRIM50;SHRPRBCK1R;RNF149;UBE2M;RAG1;MARCH5L;ZNRF2B;ITCHA |
tubulin-glutamic acid ligase activity | MYLIPB;RFWD2;RAG1;RNF169;TTLL1;LTN1;NEURL1B;ZNRF3;MARCH11 |
tubulin-glycine ligase activity | ITCHA;HECW2;RFWD2;RAG1;MARCH11;RNF144AA;MARCH5L;UBR1;G2E3 |
ubiquitin protein ligase binding | CUL3A;HIF1A;UBE2NB;SMAD3;PRDX6;RRAGA;SUMO2;UBE2G1;CHEK2 |
zinc ion binding | DYTN;JHDM1D;TRIM43A;BTR18;MEP1B;ZNRF2;TRIM2A;RFPL4;TRIM35-34 |
DTX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX1.
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