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DTX2

  • Official Full Name

    deltex homolog 2 (Drosophila)

  • Overview

    DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
  • Synonyms

    DTX2; deltex homolog 2 (Drosophila); deltex (Drosophila) homolog 2; protein deltex-2; RNF58; Deltex 2; Deltex2; hDTX2; Highly similar to hPMSR6 [H.sapiens]; Protein deltex 2; RING finger protein 58; Zinc ion binding protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DTX2-12191H Recombinant Human DTX2, GST-tagged E.coli GST C-term-253a.a.
Human DTX2-513HCL Recombinant Human DTX2 cell lysate N/A
Human DTX2-2714H Recombinant Human DTX2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DTX2-1319H Recombinant Human DTX2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DTX2-191H Recombinant Human DTX2 protein, His-tagged E. coli His 1-253 aa
Human DTX2-30126H Recombinant Human DTX2 protein, GST-tagged E.coli GST Met1-Gln253
Human DTX2-6535H Recombinant Human DTX2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse DTX2-4857M Recombinant Mouse DTX2 Protein Mammalian Cell His
Mouse Dtx2-2673M Recombinant Mouse Dtx2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DTX2-2549M Recombinant Mouse DTX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse DTX2-2549M-B Recombinant Mouse DTX2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish DTX2-6778Z Recombinant Zebrafish DTX2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DTX2 Related Articles

DTX2 involved in several pathways and played different roles in them. We selected most pathways DTX2 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Notch Signaling Pathway, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activated NOTCH1 Transmits Signal to the NucleusCNTN1;DLK1;JAG1;DNER;DTX2;ADAM10;JAG2;MIB1
Notch Signaling PathwayMARK2;DLC;RBPJ;DLK1;DLL3;SNW1;HER12;KAT2B;ADAM17A
Signal TransductionFFAR3;NEDD8L;PLEKHG2;UTS2D;CD97;GPR120;ADH8B;RGS9BP;ARHGEF18A
Signaling by NOTCHDNER;TLE3;MDKB;TLE2;MDK;DLK1;DTX2;MDKA;HEYL
Signaling by NOTCH1DLK1;TLE3;DTX2;HEYL;DNER

DTX2 has several biochemical functions, for example, ligase activity, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX2 itself. We selected most functions DTX2 had, and list some proteins which have the same functions with DTX2. You can find most of the proteins on our site.

Function Related Protein
ligase activityMUL1;TTLL11;STUB1;RNF40;PELI3;ARIH1L;MSL2;RNF6;RBCK1
protein bindingTP53;CRTC1;CTSD;KRT40;KRTAP9-4;ZBTB7B;RAI1;SART1;PARK7
zinc ion bindingZSWIM3;CPA2;ZMIZ1;MMP17;PEX2;NPLOC4;SRSF7B;ZFAND2B;PDZRN4

DTX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX2.

UBE2D4; NCALD; NCS1; VSNL1

Blanco, J; Arevalo, F; et al. Effect of the industrial steaming on the toxicity, estimated by LC-MS/MS, of mussels exposed for a long time to diarrhetic shellfish poisoning (DSP) toxins. FOOD CHEMISTRY 177:240-247(2015).
Garcia-Mendoza, E; Sanchez-Bravo, YA; et al. Lipophilic toxins in cultivated mussels (Mytilus galloprovincialis) from Baja California, Mexico. TOXICON 90:111-123(2014).
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