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DTX3L

  • Official Full Name

    deltex 3-like

  • Overview

    DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 (PubMed 12670957)).
  • Synonyms

    DTX3L; deltex 3-like (Drosophila); E3 ubiquitin-protein ligase DTX3L; BBAP; rhysin 2; rhysin2; rhysin-2; B-lymphoma- and BAL-associated protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DTX3L-2909H Recombinant Human DTX3L Protein, GST-tagged Wheat Germ GST
Human DTX3L-12193H Recombinant Human DTX3L, GST-tagged E.coli GST C-term-311a.a.
Human DTX3L-6792HCL Recombinant Human DTX3L 293 Cell Lysate HEK293 N/A
Human DTX3L-4478H Recombinant Human DTX3L Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DTX3L-0448H Recombinant Human DTX3L Protein (A2-E740), Tag Free E.coli No tag A2-E740
Human DTX3L-4071HF Recombinant Full Length Human DTX3L Protein, GST-tagged In Vitro Cell Free System GST 740 amino acids
Human DTX3L-0449H Recombinant Human DTX3L Protein (A2-E740), His tagged E.coli His A2-E740
Human DTX3L-793H Recombinant Human DTX3L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human DTX3L-793H-B Recombinant Human DTX3L Protein Pre-coupled Magnetic Beads HEK293
Human DTX3L-1760HFL Recombinant Full Length Human DTX3L Protein, C-Flag-tagged Mammalian cells Flag
Mouse DTX3L-4859M Recombinant Mouse DTX3L Protein Mammalian Cell His
Mouse DTX3L-2551M Recombinant Mouse DTX3L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dtx3l-2674M Recombinant Mouse Dtx3l Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DTX3L-2551M-B Recombinant Mouse DTX3L Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DTX3L Related Articles

DTX3L involved in several pathways and played different roles in them. We selected most pathways DTX3L participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTX3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemPJA1;TRIM63;TRAT1;FCGR1B;CD300C;LCP2A;PVRL2L;FRS2A;KLC3
Antigen processing: Ubiquitination &ampDTX3L;TPP2;ARIH2;HECTD3;TRIM50;PJA2;RBCK1;RNF19B;TRIM39
Proteasome degradationRNF4;ASB4;RNF41;RNF25;UFL1;RNF123;ASB10;MKRN1;SPSB1
Class I MHC mediated antigen processing &ampCTSS;RNF6;UBA5;FBXO3;PJA1;UBE2L6;UBE2U;RNF34;B2ML
presentationSEC23A;TRAF7;LRR1;TPP2;UFL1;RNF138;TRIM63;FBXO44;LRRC41
Immune SystemHLA-DQB2;SUGT1;IFIT12;LGALS3;UNC93B1;KIF3C;CTSLL;KPNA5;GBP5
Notch Signaling PathwayNOTCH1;RFNG;PSEN2;MYCBP;HER6;HDAC2;NOTCH1A;CTBP2A;MAML1

DTX3L has several biochemical functions, for example, histone binding, ligase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DTX3L itself. We selected most functions DTX3L had, and list some proteins which have the same functions with DTX3L. You can find most of the proteins on our site.

Function Related Protein
histone bindingASF1B;IPO7;TBL1XR1;AIRE;CTSL2;HAT1;Ctsl;NAP1L2;HIST1H4B
ligase activityTRIM68;ZFP91;NEDD4;MARCH5L;TRIM69;SHPRH;STUB1;SYVN1;RNF146
protein bindingINTS12;IRF2BP1;MAP4K5;KTI12;GOLGA8G;KRT4;STRN;MFN2;HBB
ubiquitin-protein transferase activityCMTM2A;CNOT4B;UBE3A;SHPRH;FBXO22;FBXL6;RNF168;RNF141;RLIM
zinc ion bindingP2RX4;YY1;ESRRG;LIMD2;LIMS2;VDRA;TLL2;RNF32;LRSAM1

DTX3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTX3L here. Most of them are supplied by our site. Hope this information will be useful for your research of DTX3L.

SPG21; HIP2; UBE2D1; UBE2E1; UBE2D3; UBE2H; UBE2D2; UBE2I; RNF111; UBE2R2; UBE2E3; UBE2W; UBE2E2; PHF7; TRIM9; UBE2D4; MCM7

Holleman, J; Marchese, A; et al. The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4. MOLECULAR BIOLOGY OF THE CELL 25:1892-1904(2014).
Bachmann, SB; Frommel, SC; et al. DTX3L and ARTD9 inhibit IRF1 expression and mediate in cooperation with ARTD8 survival and proliferation of metastatic prostate cancer cells. MOLECULAR CANCER 13:-(2014).
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