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DTYMK

  • Official Full Name

    deoxythymidylate kinase (thymidylate kinase)

  • Overview

    Thymidylate kinase also known as deoxythymidylate kinase or dTMP kinase is an enzyme that in humans is encoded by the DTYMK gene. and belongs to thymidylate kinase family of proteins.
  • Synonyms

    DTYMK; deoxythymidylate kinase (thymidylate kinase); thymidylate kinase; CDC8; dTMP kinase; thymidylate (dTMP) kinase; TMPK; TYMK; PP3731; FLJ44192; MGC198617;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DTYMK-28069TH Recombinant Human DTYMK, His-tagged E.coli His 212 amino acids
Human DTYMK-3562H Recombinant Human DTYMK, His-tagged E.coli His
Human DTYMK-12195H Recombinant Human DTYMK, His-tagged E.coli His 1-212a.a.
Human DTYMK-2911H Recombinant Human DTYMK Protein, GST-tagged Wheat Germ GST
Human DTYMK-6791HCL Recombinant Human DTYMK 293 Cell Lysate HEK293 N/A
Human DTYMK-725H Recombinant Human DTYMK Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DTYMK-20H Recombinant Active Human DTYMK Protein, GST-tagged Insect Cell GST
Human DTYMK-2829H Recombinant Human DTYMK protein, GST-tagged E.coli GST 1-212aa
Human DTYMK-2003H Recombinant Human DTYMK Protein (Met1-Lys212), C-His tagged Mammalian cells C-His Met1-Lys212
Human DTYMK-4072HF Recombinant Full Length Human DTYMK Protein, GST-tagged In Vitro Cell Free System GST 212 amino acids
Human DTYMK-2005H Recombinant Human DTYMK Protein (Pro43-Asp190), N-His tagged E.coli N-His Pro43-Asp190
Mouse DTYMK-4861M Recombinant Mouse DTYMK Protein Mammalian Cell His
Mouse Dtymk-8232M Recombinant Mouse Dtymk protein, His & T7-tagged E.coli His/T7 Pro43~Glu190 (Accession # P97930)
Mouse DTYMK-2553M-B Recombinant Mouse DTYMK Protein Pre-coupled Magnetic Beads HEK293
Mouse DTYMK-2553M Recombinant Mouse DTYMK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dtymk-2675M Recombinant Mouse Dtymk Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Dtymk-8233R Recombinant Rat Dtymk protein, His & T7-tagged E.coli His/T7 Pro43~Glu190 (Accession # D3ZUJ5)
Rhesus Macaque DTYMK-1344R Recombinant Rhesus monkey DTYMK Protein, His-tagged Mammalian Cell His
Rhesus Macaque DTYMK-1169R-B Recombinant Rhesus Macaque DTYMK Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DTYMK-1169R Recombinant Rhesus Macaque DTYMK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DTYMK-3479Z Recombinant Zebrafish DTYMK Mammalian Cell His
Chicken DTYMK-5406C Recombinant Chicken DTYMK Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DTYMK Related Articles

DTYMK involved in several pathways and played different roles in them. We selected most pathways DTYMK participated on our site, such as Metabolic pathways, Metabolism, Metabolism of nucleotides, which may be useful for your reference. Also, other proteins which involved in the same pathway with DTYMK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolic pathwaysIMPDH1B;LIPT1;COX5A;LASS1;ASAH2;AFMID;CELL;DPYD;FPGS
MetabolismNFYBB;PDP2;KCNC2;SLC5A2;CKMT2A;ELA2;MED23;SACM1LB;CTRC
Metabolism of nucleotidesDTYMK;NUDT5;AK7;UPP2;ADSSL1;DPYDA.1;NUDT15;GLRX;ITPA
Pyrimidine metabolismDUT;ZNRD1;DHODH;TXNRD2;NT5C3A;ITPA;RRM1;POLR2GL;TRR1
Synthesis and interconversion of nucleotide di- and triphosphatesGLRX;AK8;GRX2;AK7A;AK7;DTYMK
pyrimidine deoxyribonucleotide phosphorylationCMPK2;DTYMK
pyrimidine deoxyribonucleotides biosynthesis from CTP
pyrimidine deoxyribonucleotides de novo biosynthesisDUT;DTYMK

DTYMK has several biochemical functions, for example, ATP binding, nucleoside phosphate kinase activity, thymidylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DTYMK itself. We selected most functions DTYMK had, and list some proteins which have the same functions with DTYMK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingACSM2;ATAD1B;PAPSS2;TARSL2;DGKA;ATP6V1BA;NTPCR;PIP4K2B;PFAS
nucleoside phosphate kinase activityAK9;DTYMK
thymidylate kinase activityDTYMK;CMPK2
uridylate kinase activityCMPK1;CMPK;DTYMK

DTYMK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DTYMK here. Most of them are supplied by our site. Hope this information will be useful for your research of DTYMK.

HSD17B7; CDC5L

Liu, Y; Marks, K; et al. Metabolic and Functional Genomic Studies Identify Deoxythymidylate Kinase as a Target in LKB1-Mutant Lung Cancer. CANCER DISCOVERY 3:870-879(2013).
Felizardo, TC; Foley, J; et al. Harnessing autophagy for cell fate control gene therapy. AUTOPHAGY 9:1069-1079(2013).
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