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DUSP14

  • Official Full Name

    dual specificity phosphatase 14

  • Overview

    Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based;protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine;and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14;contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP;(mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009;(PubMed 19228121)).
  • Synonyms

    DUSP14; dual specificity phosphatase 14; dual specificity protein phosphatase 14; MKP 1 like protein tyrosine phosphatase; MKP L; MKP6; MKP-6; MAP kinase phosphatase 6; MKP-1 like protein tyrosine phosphatase; MKP-1-like protein tyrosine phosphatase; mito;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • MBP
  • SUMO
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DUSP14-2511H Recombinant Human DUSP14, His & MBP tagged E.coli His/MBP Met 1 –His 191
Human DUSP14-2928H Recombinant Human DUSP14 Protein, GST-tagged Wheat Germ GST
Human DUSP14-28072TH Recombinant Human DUSP14, T7 -tagged E.coli T7
Human DUSP14-853H Recombinant Human DUSP14, T7-tagged E.coli T7
Human DUSP14-6781HCL Recombinant Human DUSP14 293 Cell Lysate HEK293 N/A
Human DUSP14-4097HF Recombinant Full Length Human DUSP14 Protein, GST-tagged In Vitro Cell Free System GST 198 amino acids
Human DUSP14-4928H Recombinant Human DUSP14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DUSP14-2830H Recombinant Human DUSP14 protein, His-SUMO-tagged E.coli His-SUMO 1-198aa
Mouse Dusp14-2683M Recombinant Mouse Dusp14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque DUSP14-1349R Recombinant Rhesus monkey DUSP14 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DUSP14-1174R-B Recombinant Rhesus Macaque DUSP14 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DUSP14-1174R Recombinant Rhesus Macaque DUSP14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DUSP14-1570Z Recombinant Zebrafish DUSP14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DUSP14 involved in several pathways and played different roles in them. We selected most pathways DUSP14 participated on our site, such as Hypertrophy Model, which may be useful for your reference. Also, other proteins which involved in the same pathway with DUSP14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hypertrophy ModelCYR61;DUSP14;MYOG;HBEGFB;IFRD1;JUND;ADAM10A;WDR1;ANKRD1

DUSP14 has several biochemical functions, for example, MAP kinase tyrosine/serine/threonine phosphatase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DUSP14 itself. We selected most functions DUSP14 had, and list some proteins which have the same functions with DUSP14. You can find most of the proteins on our site.

Function Related Protein
MAP kinase tyrosine/serine/threonine phosphatase activityDUSP7;DUSP9;PTPRQ;SACM1LB;SACM1LA;DUSP14;CTDSPL2B;DUSP4;SGPP2
poly(A) RNA bindingZC3H15;UTP23;RCC2;RPS25;SLC16A3;YWHAE;DHX57;SCG3;YARS
protein bindingAP2A1;C7orf59;SPA17;RAB4B;MPLKIP;CX3CL1;TSHR;KHDRBS2;NPPA
protein tyrosine phosphatase activityPTPN11A;PTPN9;PTPRZ1;DUSP6;PTPN13;PTPRU;PTP4A2A;PALD1;CDC14C
protein tyrosine/serine/threonine phosphatase activityCDC14AA;SACM1LB;PTPDC1;PTPRQ;DUSP3B;DUSP12;PTPMT1;PTP4A1;CDC14C

DUSP14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DUSP14 here. Most of them are supplied by our site. Hope this information will be useful for your research of DUSP14.

SPERT; ISYNA1

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