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DUSP18

  • Official Full Name

    dual specificity phosphatase 18

  • Overview

    Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009
  • Synonyms

    DUSP18; dual specificity phosphatase 18; dual specificity protein phosphatase 18; DUSP20; LMWDSP20; Low molecular weight dual specificity phosphatase 20; LMW-DSP20; DSP18; bK963H5.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DUSP18-1923H Recombinant Human Dual Specificity Phosphatase 18, His-tagged His
Human DUSP18-2931H Recombinant Human DUSP18 Protein, GST-tagged Wheat Germ GST
Human DUSP18-12210H Recombinant Human DUSP18, GST-tagged E.coli GST 1-188a.a.
Human DUSP18-6780HCL Recombinant Human DUSP18 293 Cell Lysate HEK293 N/A
Human DUSP18-3932H Recombinant Human DUSP18 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DUSP18-4099HF Recombinant Full Length Human DUSP18 Protein, GST-tagged In Vitro Cell Free System GST 188 amino acids
Mouse Dusp18-2685M Recombinant Mouse Dusp18 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat DUSP18-1974R Recombinant Rat DUSP18 Protein Mammalian Cell His
Rat DUSP18-1633R Recombinant Rat DUSP18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DUSP18-1633R-B Recombinant Rat DUSP18 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DUSP18-1350R Recombinant Rhesus monkey DUSP18 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DUSP18-1175R-B Recombinant Rhesus Macaque DUSP18 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DUSP18-1175R Recombinant Rhesus Macaque DUSP18 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

DUSP18 involved in several pathways and played different roles in them. We selected most pathways DUSP18 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DUSP18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

DUSP18 has several biochemical functions, for example, MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DUSP18 itself. We selected most functions DUSP18 had, and list some proteins which have the same functions with DUSP18. You can find most of the proteins on our site.

Function Related Protein
MAP kinase tyrosine/serine/threonine phosphatase activityDUSP21;PXYLP1;DUSP18;SACM1LA;SACM1L;DUSP1;DUSP10;DUSP14;DUSP7
protein tyrosine phosphatase activitySSH2B;EYA4;PTPN6;PTP4A1;EYA1;PTPN20;PTPRK;PALD1A;DUSP21
protein tyrosine/serine/threonine phosphatase activityDUSP3B;PXYLP1;PTEN;SSH1;SSH3;CTDSPL2A;DUSP23;TPTE;DUSP3

DUSP18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DUSP18 here. Most of them are supplied by our site. Hope this information will be useful for your research of DUSP18.

MAPK8IP2

  • Q&As
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