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DYNC1I2

  • Official Full Name

    dynein, cytoplasmic 1, intermediate chain 2

  • Overview

    Cytoplasmic dynein 1 intermediate chain 2 is a protein that in humans is encoded by the DYNC1I2 gene.
  • Synonyms

    DYNC1I2; dynein, cytoplasmic 1, intermediate chain 2; DNCI2, dynein, cytoplasmic, intermediate polypeptide 2; cytoplasmic dynein 1 intermediate chain 2; DH IC 2; DNCI2; DNCIC2; Dynein intermediate chain 2, cytosolic; Dynein, cytoplasmic, intermediate polypeptide 2; IC2; DH IC-2; cytoplasmic dynein intermediate chain 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DYNC1I2-2968H Recombinant Human DYNC1I2 Protein, GST-tagged Wheat Germ GST
Human DYNC1I2-12227H Recombinant Human DYNC1I2, GST-tagged E.coli GST C-term-309a.a.
Human DYNC1I2-239HCL Recombinant Human DYNC1I2 lysate HEK293 N/A
Human DYNC1I2-4144HF Recombinant Full Length Human DYNC1I2 Protein, GST-tagged In Vitro Cell Free System GST 612 amino acids
Rhesus Macaque DYNC1I2-1359R Recombinant Rhesus monkey DYNC1I2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DYNC1I2-1184R-B Recombinant Rhesus Macaque DYNC1I2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DYNC1I2-1184R Recombinant Rhesus Macaque DYNC1I2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken DYNC1I2-1657C Recombinant Chicken DYNC1I2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DYNC1I2 Related Articles

DYNC1I2 involved in several pathways and played different roles in them. We selected most pathways DYNC1I2 participated on our site, such as Adaptive Immune System, Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNC1I2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemPJA2;TRAF7;CTSE;DTX3L;PIK3AP1;KIF3B;RNF14;LILRB2;TREML1
Anchoring of the basal body to the plasma membraneCP110;CEP152;TCTN1;ODF2;CCDC123;CEP135;DCTN1A;CDK5RAP2;CEP76
Assembly of the primary ciliumTTBK2;DYNLRB2;FBF1;MAPRE1;DCTN1A;KIF3CB;EXOC6;MARK4;CEP152
Cell CycleMPEG1.1;NINL;DKC1;LMNB1;SDCCAG8;CLASP1A;TGFB3;YWHABB;GSK3AA
Cell Cycle, MitoticPCM1;NIPBL;DBF4;ZWILCH;SMC2;TMEM188;NUF2;AURKB;NEK7
Centrosome maturationTUBB4B;ODF2B;ODF2;CEP78;DYNC1I2;DCTN2;OFD1;ACTR1A;CEP164
G2/M TransitionCENPJ;CKAP5;PCM1;TUBGCP5;TUBGCP3;CEP63;TUBG1;NINL;LIN9
Immune SystemCRTAM;PANX1;UBE2J2;SIGLEC6;PELI3;HLA-DQB2;RNF144B;ARIH2;KIF4

DYNC1I2 has several biochemical functions, for example, microtubule motor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNC1I2 itself. We selected most functions DYNC1I2 had, and list some proteins which have the same functions with DYNC1I2. You can find most of the proteins on our site.

Function Related Protein
microtubule motor activityKIF23;KIF27;KIF25;KLC1B;KIF2B;DYNC1I2;KLC1A;SMC3;KIF13B
protein bindingTRP63;ZNF227;PSMC1;LRRC4C;HORMAD1;LGALS14;ASGR2;LLGL1;SYCE1

DYNC1I2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNC1I2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNC1I2.

DYNLRB1; vpr; Dync1i2; DYNLL1; Dynll1; Dync1h1; DYNLT3; pi3p; 15-deoxy-delta(12,14; midostaurin; 1C

Cao, JJ; Lin, C; et al. Circovirus Transport Proceeds via Direct Interaction of the Cytoplasmic Dynein IC1 Subunit with the Viral Capsid Protein. JOURNAL OF VIROLOGY 89:2777-2791(2015).
Ma, C; Yao, Y; et al. Differential Proteomic Analysis of Platelets Suggested Possible Signal Cascades Network in Platelets Treated with Salvianolic Acid B. PLOS ONE 6:-(2011).
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