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DYNLRB1

  • Official Full Name

    dynein, light chain, roadblock-type 1

  • Overview

    DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
  • Synonyms

    km23; Dncl2a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DYNLRB1-2750H Recombinant Human DYNLRB1, His-tagged E.coli His
Human DYNLRB1-12233H Recombinant Human DYNLRB1, GST-tagged E.coli GST 1-96a.a.
Human DYNLRB1-273H Recombinant Human DYNLRB1 protein, His-tagged E.coli His 1 - 96 aa
Human DYNLRB1-2976H Recombinant Human DYNLRB1 Protein, GST-tagged Wheat Germ GST
Human DYNLRB1-6755HCL Recombinant Human DYNLRB1 293 Cell Lysate HEK293 N/A
Human DYNLRB1-4800H Recombinant Human DYNLRB1 protein, His-SUMO-tagged E.coli His-SUMO 3-96aa
Human DYNLRB1-1114H Recombinant Human DYNLRB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DYNLRB1-4159HF Recombinant Full Length Human DYNLRB1 Protein, GST-tagged In Vitro Cell Free System GST 22-96 amino acids
Mouse DYNLRB1-4914M Recombinant Mouse DYNLRB1 Protein Mammalian Cell His
Mouse Dynlrb1-2700M Recombinant Mouse Dynlrb1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DYNLRB1-2584M-B Recombinant Mouse DYNLRB1 Protein Pre-coupled Magnetic Beads HEK293
Mouse DYNLRB1-2584M Recombinant Mouse DYNLRB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DYNLRB1-1989R Recombinant Rat DYNLRB1 Protein Mammalian Cell His
Rat DYNLRB1-1647R-B Recombinant Rat DYNLRB1 Protein Pre-coupled Magnetic Beads HEK293
Rat DYNLRB1-1647R Recombinant Rat DYNLRB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish DYNLRB1-11405Z Recombinant Zebrafish DYNLRB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • DYNLRB1 Related Articles

DYNLRB1 involved in several pathways and played different roles in them. We selected most pathways DYNLRB1 participated on our site, such as Assembly of the primary cilium, Intraflagellar transport, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with DYNLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Assembly of the primary ciliumTMEM67;TCTN3;CEP78;KIF3CB;DYNLL2;CEP152;IFT74;CSNK1E;IFT172
Intraflagellar transportTCTEX1D2;TTC30A;IFT172;IFT46;IFT43;IFT81;TCTEX1D1;IFT-20;OST4
Organelle biogenesis and maintenanceIFT122;GADD45GIP1;MRPL52;TRAF3IP1;KIFAP3B;NPHP1;WDR35;BBS2;TTC30A2

DYNLRB1 has several biochemical functions, for example, identical protein binding, motor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DYNLRB1 itself. We selected most functions DYNLRB1 had, and list some proteins which have the same functions with DYNLRB1. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingTNN;EGFR;TMEM173;BAIAP2;CBLL1;APLP1;PLEKHH2;SEPHS1;DYNLT1C
motor activityMYH6;MYH1E;MYHZ1.1;MYH9A;DYNLT1;MYO1E;DYNLRB1;SMYHC3;DNAI1
protein bindingSCAF8;YIF1A;EPB41;UBXN2B;ACVRL1;MAGEA1;AP4M1;RPL12;POLL

DYNLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DYNLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of DYNLRB1.

DYNC1LI2; RANGAP1; DYNLT3; ACTR1A; Ywhae; DYNC1I2; DCTN2; DCTN1; DYNC1H1; UBR2; CCDC82; WDR60; WDR34; LUC7L; DYNC1LI1

Asante, D; Stevenson, NL; et al. Subunit composition of the human cytoplasmic dynein-2 complex. JOURNAL OF CELL SCIENCE 127:4774-4787(2014).
Pagaev, RM; Kakuev, DL; et al. The light chain of the dynein complex DYNLRB1 interacts with NDP-kinase a from bovine retina. DOKLADY BIOCHEMISTRY AND BIOPHYSICS 447:286-288(2012).
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